2,4-Dichloro-5-pyrimidinecarboxylic acid CAS 37131-89-8
| CAS No. | 37131-89-8 |
| Molecular Formula | C5H2Cl2N2O2 |
| Molecular Weight | 192.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,4-Dichloro-5-pyrimidinecarboxylic acid (CAS 37131-89-8), molecular formula C5H2Cl2N2O2 and molecular weight 192.99 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,4-Dichloro-5-pyrimidinecarboxylic acid (C5H2Cl2N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2,4-Dichloro-5-pyrimidinecarboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2Cl2N2O2 |
| Molecular Weight | 192.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2,3-Dichloro-4-nitropyridine (CAS 1360438-45-4)
- 2,4-Dichloro-6-nitropyridine (CAS 1379337-73-1)
- 2,5-Dichloro-4-nitropyridine (CAS 1400701-63-4)
- 3,6-Dichloro-2-nitropyridine (CAS 1422434-67-0)
- 4,5-Dichloro-2-nitropyridine (CAS 1803781-87-4)
- 2,3-Dichloro-6-nitropyridine (CAS 1807182-32-6)
- 2,3-Dichloro-5-nitropyridine (CAS 22353-40-8)
- 2,4-Dichloro-3-nitropyridine (CAS 5975-12-2)
Recommended Standards
- 2,4-Dichloro-5-nitropyridine (CAS 4487-56-3)
- 2,5-Dichloro-3-nitropyridine (CAS 21427-62-3)
- 2,6-Dichloro-4-nitropyridine (CAS 25194-01-8)
- 2-Bromo-1,4-difluorobenzene (CAS 399-94-0)
- 2-(4-Bromo-2-formylphenoxy)-N-(2,5-dimethylphenyl)acetamide (CAS 552841-81-3)
- cis-Dichlorodicarbonylplatinum(II), (99.9%-Pt) (CAS 25478-60-8)
- Benzaldehyde, 2-(benzyloxy)-3-methoxy- (CAS 2011-06-5)
- 3,3,6-Trifluoroindolin-2-one (CAS 1393544-05-2)
- Methyl 2-(quinoxalin-5-yl)acetate (CAS 1383625-69-1)
- Ferulic Acid Impurity 2 (CAS 1014-83-1)
- 1-Cyclopropoxy-3-nitro-2-(trifluoromethyl)benzene (CAS 1243325-35-0)
- 2,3,5-Trifluoro-4-hydroxybenzaldehyde (CAS 676500-50-8)
- (2,2,2-Trifluoroethyl)hydrazine 2hcl (CAS 1251922-77-6)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
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