Ethyl 3-Amino-4,4,4-trifluorocrotonate CAS 372-29-2
| CAS No. | 372-29-2 |
| Molecular Formula | C6H8F3NO2 |
| Molecular Weight | 183.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 3-Amino-4,4,4-trifluorocrotonate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Ethyl 3-Amino-4,4,4-trifluorocrotonate (CAS 372-29-2), molecular formula C6H8F3NO2 and molecular weight 183.13 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 3-Amino-4,4,4-trifluorocrotonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8F3NO2 |
| Molecular Weight | 183.13 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 1,3,5-TRIFLUORO-2-NITROBENZENE 2,2,6-TRIFLUORONITROBENZENE 2,4,6-TRIFLUORONITROBENZENE 2-NITRO-1,3,5-TRIFLUOROBENZENE 315-14-0 PF10378 (CAS 315-14-0)
- 2,3,5-Trifluoroisonicotinic acid 2,3,5-trifluoropyridine-4-carboxylic acid 675602-91-2 (CAS 675602-91-2)
- Ethyl (E)-3-Amino-4,4,4-trifluoro-2-butenoate (CAS 498583-09-8)
- D-Mannose-1,2,3-13C3 (CAS CATO-CCFD202473)
- 2804-50-4 A819298 [4,5-diacetyloxy-2-methyl-6-(6-oxidanylidene-3H-purin-9-yl)oxan-3-yl] ethanoate acetic acid [4,5-diacetyloxy-2-methyl-6-(6-oxo-3H-purin-9-yl)-3-oxanyl] ester (CAS 2804-50-4)
- Tert-butyl 1-fluoro-5-methoxy-3-azabicyclo[3.1.1]Heptane-3-carboxylate (CAS 2413900-24-8)
- 4-(Phenylthio)butane-1-sulfonyl chloride (CAS 1375068-15-7)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(trifluoromethyl)-1H-pyrazole (CAS 1046831-98-4)
- 2-Amino-1-[4-(4-chlorophenyl)piperazin-1-yl]ethan-1-one (CAS 770699-74-6)
- Ixazomib Impurity 35 (CAS CATO-C4X-126735)
- 1-(4-Fluorophenyl)-3-(propan-2-yloxy)propan-2-one (CAS 1158037-45-6)
- 178483-14-2 3-(1-Naphthyl)pyrrolidine 5967AD C14H15N (CAS 178483-14-2)
- 2-((4-Ethylpiperazin-1-yl)methyl)azepane oxalate (CAS 1177325-15-3)
- Dulaglutide (CAS 923950-08-7)
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