Ethyl 2-(2-fluoroethoxy)acetate CAS 372-51-0
| CAS No. | 372-51-0 |
| Molecular Formula | C6H11FO3 |
| Molecular Weight | 150.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 2-(2-fluoroethoxy)acetate (CAS 372-51-0) is a high-purity analytical reference standard with the molecular formula C6H11FO3 and a molecular weight of 150.15 g/mol.
Structurally, Ethyl 2-(2-fluoroethoxy)acetate (C6H11FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 150.15 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H11FO3 |
| Molecular Weight | 150.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 2-(2-Fluoroethoxy)tetrahydro-2H-pyran (CAS 111860-35-6)
- 2-(2-(2-Fluoroethoxy)ethoxy)ethan-1-ol (CAS 373-45-5)
- 4-(2-Fluoroethoxy)piperidine (CAS 1220179-26-9)
- 1,2-Bis(2-Fluoroethoxy)Ethane (CAS 63938-33-0)
- 1-(2-Fluoroethoxy)-2-methylbenzene (CAS 123644-37-1)
- 2-(2-Fluoroethoxy)aniline (CAS 1547-11-1)
- 4-(2-Fluoroethoxy)aniline (CAS 1547-12-2)
- 3-(2-Fluoroethoxy)aniline (CAS 1764-82-5)
Recommended Standards
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- 1-(2-Fluorophenoxy)cyclopropane-1-carboxylic acid (CAS 1399659-67-6)
- 4-(2,4-Dimethylphenyl)-2-fluorophenol (CAS 1261978-86-2)
- 1,2,3,4-Tetrahydroisoquinoline-7-sulfonyl fluoride (CAS 76258-59-8)
- (2-(2,2,2-Trifluoroethoxy)thiazol-5-yl)methanamine (CAS 1003853-96-0)
- 3-Chloro-5-(5-nitrofuran-2-yl)-1H-1,2,4-triazole (CAS 41735-54-0)
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