5-(Pyridin-3-yl)-1,3-thiazol-2-amine CAS 372096-52-1
| CAS No. | 372096-52-1 |
| Molecular Formula | C8H7N3S |
| Molecular Weight | 177.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-(Pyridin-3-yl)-1,3-thiazol-2-amine (CAS 372096-52-1), a certified reference material (molecular formula C8H7N3S, MW 177.23 g/mol) for analytical method development and quality control.
The molecular framework of 5-(Pyridin-3-yl)-1,3-thiazol-2-amine (C8H7N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7N3S |
| Molecular Weight | 177.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pyridin Standards
- 2-(Pyridin-3-yl)thiazol-5-amine (CAS 1159821-51-8)
- 5-(Pyridin-2-yl)-1,3-thiazol-2-amine (CAS 1215073-56-5)
- 2-(Pyridin-3-yl)thiazol-4-amine (CAS 123970-76-3)
- 1-(Pyridin-2-yl)-1H-pyrazole-4-thiol (CAS 1429903-03-6)
- 5-(Pyridin-4-yl)-1H-imidazole-2-thiol (CAS 146366-04-3)
- 1-(Pyridin-3-yl)-1H-imidazole-2-thiol (CAS 17452-15-2)
- 2-(Pyridin-2-yl)-1,3-thiazol-4-amine (CAS 93209-74-6)
- 2-(Pyridin-4-yl)thiazol-4-amine (CAS 89401-67-2)
Recommended Standards
- 4-Phenyl-1,2,5-thiadiazol-3-amine (CAS 33710-58-6)
- 5-(Pyridin-4-yl)thiazol-2-amine (CAS 40353-55-7)
- 4-Cyanophenylthiourea (CAS 3460-55-7)
- 5-(Thiophen-3-yl)pyrazin-2-amine (CAS 710323-21-0)
- 2-(tert-Butoxy)-5-cyclopropoxy-N,N-dimethylaniline (CAS 1243323-93-4)
- tert-Butyl 3-(bromomethyl)-5-nitro-1H-indazole-1-carboxylate (CAS 942189-50-6)
- (2,3-Difluoro-4-(4-methylpiperidin-1-yl)phenyl)boronic acid (CAS 1704069-62-4)
- Cenobamate impurity 13-D3 (CAS CATO-C4X-241613)
- Crisaborole lmpurity 86 (CAS CATO-C4X-202186)
- 2-(6-Bromo-5-fluoropyridin-3-yl)acetic acid (CAS 1227593-08-9)
- 4,5-Dimethyl-2-(2H-tetrazol-2-yl)thiophene-3-carboxylic acid (CAS 2090324-68-6)
- 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxychroman-4-one (CAS 17060-20-7)
- 4-(4-Chloro-3-methyl-1h-pyrazol-1-yl)butanoic acid (CAS 1006453-31-1)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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