3-(6-(Trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl)benzonitrile CAS 372122-60-6
| CAS No. | 372122-60-6 |
| Molecular Formula | C15H8F3N3 |
| Molecular Weight | 287.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(6-(Trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl)benzonitrile (C15H8F3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 3-(6-(Trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl)benzonitrile (CAS 372122-60-6), a certified reference material (molecular formula C15H8F3N3, MW 287.24 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(6-(Trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl)benzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H8F3N3 |
| Molecular Weight | 287.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 4-(5-Methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)morpholine (CAS 900900-01-8)
- 4-(6-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)benzonitrile (CAS 907960-23-0)
- 4-(8-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)benzonitrile (CAS 1980053-08-4)
- 6-(Trifluoromethyl)benzo[4,5]imidazo[1,2-c]quinazoline (CAS 70371-94-7)
- 5-Oxo-1-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidine-3-carboxylic acid (CAS 1016499-07-2)
- 5-Oxo-1-[4-(trifluoromethyl)benzyl]pyrrolidine-3-carboxylic acid (CAS 253178-82-4)
- Methyl 2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxylate (CAS 1018975-69-3)
- 4-Methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid (CAS 144059-85-8)
Recommended Standards
- 2-Isopropyl-1-methyl-5-nitro-6-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 61680-11-3)
- 4-(3,4-Dimethoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-amine (CAS 384811-13-6)
- Methyl 7-isopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate (CAS 1798723-27-9)
- 4-(3,4,5-Trifluorobenzoyl)quinoline (CAS 1706462-49-8)
- n-Benzyl-3-morpholinopropan-1-amine (CAS 2038-06-4)
- 3-Cyclopropylthiophene-2-carbaldehyde (CAS 29481-31-0)
- 4-(Chloromethyl)-2-(3-ethylphenyl)thiazole (CAS 1393576-93-6)
- 2,2,2-Trichloro-1-(1-methyl-1H-1,2,4-triazol-5-yl)ethan-1-one (CAS 131758-17-3)
- rac-[(2R,3R)-1-cyclopropyl-2-(1-methyl-1H-imidazol-5-yl)piperidin-3-yl]methanol (CAS 1969288-14-9)
- Cyclopropyl(3-(methylthio)-8-azabicyclo[3.2.1]octan-8-yl)methanone (CAS 1795416-39-5)
- 2-Propylpyridin-3-ol (CAS 14159-68-3)
- Isoquinoline-7-carboxamide (CAS 1158755-26-0)
- N-(2,4-dichlorophenyl)benzamide (CAS 10286-76-7)
- Glucagon Monohydrochloride (CAS 28270-04-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com