2-Chloro-4-(4-fluorophenethyl)-6-methylpyrimidine CAS 372183-70-5
| CAS No. | 372183-70-5 |
| Molecular Formula | C13H12ClFN2 |
| Molecular Weight | 250.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 2-Chloro-4-(4-fluorophenethyl)-6-methylpyrimidine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 250.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-Chloro-4-(4-fluorophenethyl)-6-methylpyrimidine (CAS 372183-70-5) is a high-purity analytical reference standard with the molecular formula C13H12ClFN2 and a molecular weight of 250.70 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-4-(4-fluorophenethyl)-6-methylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12ClFN2 |
| Molecular Weight | 250.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-6-(4-fluorobenzyl)-4,5-dimethylpyridazine (CAS 1057682-70-8)
- 2-Chloro-N-(2-methoxyethyl)pyridine-3-sulfonamide (CAS 1155913-04-4)
- Methyl 4-chloro-2-((2-hydroxypropyl)amino)thiazole-5-carboxylate (CAS 1184498-64-3)
- 4-Chloro-2-(2-fluorophenyl)-6-isopropylpyrimidine (CAS 1239848-59-9)
- 5-Chloro-4-propoxypyridine-3-sulfonamide (CAS 1352506-61-6)
- 5-Chloro-N-ethyl-4-hydroxy-N-methylpyridine-3-sulfonamide (CAS 1352515-19-5)
- 5-Chloro-4-(isopropylamino)pyridine-3-sulfonic acid (CAS 1352516-05-2)
- 5-Chloro-4-(propylamino)pyridine-3-sulfonic acid (CAS 1352521-98-2)
Recommended Standards
- 2-(Methoxymethoxy)-6-methylbenzenesulfonyl chloride (CAS 2138186-74-8)
- 2-Chloro-6-fluorobenzyl)(pyridin-4-ylmethyl)amine (CAS 774554-66-4)
- 2-(Chloromethyl)-4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-4-one (CAS 62773-11-9)
- 2-chloro-N-[2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethyl]propanamide (CAS 879361-55-4)
- <I>N</I>-[(1<I>R</I>,2<I>R</I>)-2-(1-piperidinyl)cyclohexyl]-<I>N< /I>′-[4-(trifluoromethyl)phenyl]tetraamide (CAS 1211565-08-0)
- n-(1-(2,4-Difluorophenyl)ethyl)butan-1-amine (CAS 1019566-37-0)
- Ethyl 3-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)propanoate (CAS 98354-17-7)
- Avanafil Impurity 131 (CAS CATO-C4X-1118131)
- 2-(4-Methoxyphenoxy)benzenecarbaldehyde oxime (CAS 449778-55-6)
- {1-[(3,4-dichlorophenyl)methyl]piperidin-2-yl}methanol (CAS 1261235-70-4)
- tert-Butylferrocene (CAS 1316-98-9)
- cis-3-methoxycyclopentanamine (CAS 1268522-02-6)
- Boc-Gly-Gly-N-[4-(hydroxymethyl)phenyl] (CAS 251459-35-5)
- Insulin degludec (CAS 844439-96-9)
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