2-Amino-4-(hydroxymethyl)thiazole Hydrochloride CAS 372509-58-5
| CAS No. | 372509-58-5 |
| Molecular Formula | C4H6N2OS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 166.62 g/mol gives 2-Amino-4-(hydroxymethyl)thiazole Hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-4-(hydroxymethyl)thiazole Hydrochloride (CAS 372509-58-5) is a high-purity analytical reference standard with the molecular formula C4H6N2OSHCl and a molecular weight of 166.62 g/mol.
The molecular framework of 2-Amino-4-(hydroxymethyl)thiazole Hydrochloride (C4H6N2OSHCl) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-4-(hydroxymethyl)thiazole Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H6N2OS HCl |
| Molecular Weight | 166.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- 3-Carboethoxy-3-(2-thiomethylphenyl)propiophenone (CAS 898754-42-2)
- RevefenacinTrihydrate (CAS CATO-C4X-203171)
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