1-(4-Fluorophenyl)-1,3-dihydro-3-oxo-5-isobenzofurancarboxylic Acid CAS 372941-51-0
| CAS No. | 372941-51-0 |
| Molecular Formula | C15H9FO4 |
| Molecular Weight | 272.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(4-Fluorophenyl)-1,3-dihydro-3-oxo-5-isobenzofurancarboxylic Acid (CAS 372941-51-0), molecular formula C15H9FO4 and molecular weight 272.23 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, 1-(4-Fluorophenyl)-1,3-dihydro-3-oxo-5-isobenzofurancarboxylic Acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 272.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H9FO4 |
| Molecular Weight | 272.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- [7-(4-fluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]acetic acid (CAS 1160245-79-3)
- 2-(4-Fluorophenyl)-7-methyl-5-nitrobenzo[d]oxazole (CAS 1421240-95-0)
- 2-(4-Fluorophenyl)-5,7-dihydroxy-4H-chromen-4-one (CAS 152969-67-0)
- 3-(4-Fluorophenyl)-5,7-dihydroxy-4H-chromen-4-one (CAS 15584-09-5)
- 1-(2-Fluorophenyl)-5-(1H-pyrrol-1-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1710845-82-1)
- 2-(3-Fluorophenyl)-5,7-dihydroxy-4H-chromen-4-one (CAS 957131-86-1)
- 6-(2-Fluorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 924129-81-7)
- 6-(4-Fluorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 923909-95-9)
Recommended Standards
- (R)-3-(Trifluoromethyl)-7,8,9,10-tetrahydro-5H-pyrazino[1,2-a]pyrido[3,2-e]pyrazin-6(6aH)-one (CAS 2817667-47-1)
- 1-[3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazine (CAS 338748-56-4)
- m-PEG4-phosphonic acid (CAS 1872433-62-9)
- 4-Fluoro-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoic acid (CAS 2142574-09-0)
- 2,7-Dichlorofluorenyl Bromomethyl Ketone (CAS 53221-22-0)
- 2-[(4-Aminophenyl)propan-2-yl]-4-thiazolecarboxylic Acid Hydrochloride (CAS 1538680-70-4)
- Ethyl 4-(tributylstannyl)benzoate (CAS 294210-67-6)
- (4-Methoxy-2,5-dimethylbenzyl)(2-phenylethyl)amine (CAS 355383-21-0)
- N-(1-morpholinopropan-2-yl)thietan-3-amine (CAS 1882802-09-6)
- 5-Fluoro-2-nitrobenzaldehyde (CAS 395-81-3)
- 2-(4-(4-Chlorophenyl)thiazol-2-yl)ethan-1-amine (CAS 641993-24-0)
- N-(2-Chlorophenyl)-1-(2-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide (CAS 890645-66-6)
- (S)-2-(4-Fluorophenyl)pyrrolidine hydrochloride (CAS 1073556-40-7)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
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