(E)-N'-(2,2-dimethylpropylidene)benzohydrazide CAS 372960-11-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-N'-(2,2-dimethylpropylidene)benzohydrazide.

(E)-N'-(2,2-dimethylpropylidene)benzohydrazide (CAS 372960-11-7), molecular formula C12H16N2O and molecular weight 204.27 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, (E)-N'-(2,2-dimethylpropylidene)benzohydrazide is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 204.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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