Methyl 2-(3,4-dichlorobenzylidene)-5-(3,4-dimethoxyphenyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate CAS 372970-66-6
| CAS No. | 372970-66-6 |
| Molecular Formula | C24H20Cl2N2O5S |
| Molecular Weight | 519.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2-(3,4-dichlorobenzylidene)-5-(3,4-dimethoxyphenyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate.
Methyl 2-(3,4-dichlorobenzylidene)-5-(3,4-dimethoxyphenyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 372970-66-6) is a high-purity analytical reference standard with the molecular formula C24H20Cl2N2O5S and a molecular weight of 519.40 g/mol.
Structurally, Methyl 2-(3,4-dichlorobenzylidene)-5-(3,4-dimethoxyphenyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (C24H20Cl2N2O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 519.40 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H20Cl2N2O5S |
| Molecular Weight | 519.40 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- 4-(5-(3,5-dihydroxyphenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)benzamide (CAS CATO-C4X-218055)
- Mometasone Furoate Impurity 11 (CAS CATO-C4X-170411)
- Itraconazole Impurity 99 (CAS CATO-C4X-149799)
- 2-[1-(3,4-Dichlorobenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile (CAS 1144853-65-5)
- 1,6-bis-(CYCLOHEXYLOXIMINO- CARBONYLAMINO)-HEXANE (CAS 83654-05-1)
- Ethyl 5-(p-tolylthio)-1,2,3-thiadiazole-4-carboxylate (CAS 306977-04-8)
- 5,6,7,8-Tetrahydronaphthalene-2-sulfonic acid (CAS 93-12-9)
- 1-(Benzyloxy)-1H-imidazole-2-carbaldehyde (CAS 202211-96-9)
- 2-(1-Benzyl-3,5-dimethyl-1h-pyrazol-4-yl)ethan-1-amine (CAS 1017789-11-5)
- 3-Methylcrotonic Acid (CAS 541-47-9)
- Felodipine Impurity 9 (CAS CATO-C4X-10949)
- (4-Fluoro-6-(1H-pyrrol-1-yl)pyridin-3-yl)boronic acid (CAS 2225154-76-5)
- 3-O-ALlyl-1,2-o-isopropylidene-alpha-d-galactofuranose (CAS 1423018-05-6)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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