8-Nitro-2,3,4,5-tetrahydro-1H-benzo[c]azepine hydrochloride CAS 373385-03-6
| CAS No. | 373385-03-6 |
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-Nitro-2,3,4,5-tetrahydro-1H-benzo[c]azepine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 8-Nitro-2,3,4,5-tetrahydro-1H-benzo[c]azepine hydrochloride (CAS 373385-03-6), a certified reference material (molecular formula C10H12N2O2HCl, MW 228.68 g/mol) for analytical method development and quality control.
Structurally, 8-Nitro-2,3,4,5-tetrahydro-1H-benzo[c]azepine hydrochloride (C10H12N2O2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 228.68 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Nitro-2,3,4,5-tetrahydro-1H-benzo[c]azepine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O2 HCl |
| Molecular Weight | 228.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Nitro Standards
- 4-Nitro-2-propylbenzo[d]oxazole (CAS 1000018-05-2)
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Recommended Standards
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- 2-chloro-6-methoxy-pyridin-4-amine (CAS 1008304-85-5)
- 5-Bromo-2-(naphthalen-2-yl)isoindoline-1,3-dione (CAS 82104-05-0)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
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