2-Methyl-2-(trifluoromethyl)oxirane CAS 374-11-8
| CAS No. | 374-11-8 |
| Molecular Formula | C4H5F3O |
| Molecular Weight | 126.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Methyl-2-(trifluoromethyl)oxirane (CAS 374-11-8) is a high-purity analytical reference standard with the molecular formula C4H5F3O and a molecular weight of 126.08 g/mol.
The molecular framework of 2-Methyl-2-(trifluoromethyl)oxirane (C4H5F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Methyl-2-(trifluoromethyl)oxirane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H5F3O |
| Molecular Weight | 126.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
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Recommended Standards
- 2,3,3-trifluorocyclobutan-1-ol (CAS 2166734-44-5)
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- 5-Cyclohexyloxazolidin-2-one (CAS 1000374-94-6)
- 4-[(2-Bromoacetyl)amino]-N-ethyl-N-(1-naphthyl)-benzamide (CAS 1138443-38-5)
- (3S,5R)-piperidine-3,5-dicarboxylic acid (CAS 876367-84-9)
- Ozagrel Impurity 12 (CAS 74003-18-2)
- 2-(4-Bromo-5-methyl-3-nitro-1H-pyrazol-1-yl)acetic acid (CAS 345637-67-4)
- 5-(3,4,5-Trimethoxyphenyl)-1H-pyrazol-3-amine (CAS 502133-05-3)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
Why CATO?
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