3-Nitro-2-(piperazin-1-yl)benzoic acid CAS 374063-97-5
| CAS No. | 374063-97-5 |
| Molecular Formula | C11H13N3O4 |
| Molecular Weight | 251.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Nitro-2-(piperazin-1-yl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-Nitro-2-(piperazin-1-yl)benzoic acid (CAS 374063-97-5), a certified reference material (molecular formula C11H13N3O4, MW 251.24 g/mol) for analytical method development and quality control.
The molecular framework of 3-Nitro-2-(piperazin-1-yl)benzoic acid (C11H13N3O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H13N3O4 |
| Molecular Weight | 251.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Nitro Standards
- 3-Nitro-4-(piperazin-1-yl)benzoic acid (CAS 1216416-11-3)
- 4-(2-(4-Nitro-1-oxy-pyridin-3-yl)-vinyl)-morpholine (CAS 148760-46-7)
- 5-Nitro-2-(piperazin-1-yl)benzoic acid (CAS 168123-39-5)
- Methyl 5-nitro-6-(pyrrolidin-1-yl)pyridine-3-carboxylate (CAS 1820639-75-5)
- 2-Nitro-5-(piperazin-1-yl)benzoic acid (CAS 183622-35-7)
- 4-(4-nitro-phenyl)-3-oxo-butyric acid ethyl ester (CAS 62088-12-4)
- Ethyl(2-nitro-4-(trifluoromethyl)phenyl)sulfane (CAS 22057-35-8)
- Methyl 1-((4-nitro-1H-pyrazol-1-yl)methyl)-1H-pyrazole-3-carboxylate (CAS 1005696-77-4)
Recommended Standards
- 3-Methyl-5-((2-oxooxazolidin-5-yl)methoxy)benzoic acid (CAS 5057-74-9)
- 4-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)amino)-4-oxobutanoic acid (CAS 331461-05-3)
- 3-Hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzoic acid (CAS 240431-49-6)
- 4-((2,4-Dimethoxyphenyl)amino)-4-oxobut-2-enoic acid (CAS 496011-39-3)
- 2-Iodo-3-methoxypyrazine, 97% (CAS 58139-04-1)
- Hexahydrocoumarin (CAS 700-82-3)
- n-(Cyclopropylmethyl)-3-(methylsulfonyl)aniline (CAS 1178917-14-0)
- ethyl 3-chlorofuran-2-carboxylate (CAS 1478503-50-2)
- 4-Hydrazinyl-8-methoxy-2-methylquinoline hydrochloride (CAS 1171435-31-6)
- 5-Bromo-6-pyrrolidin-1-yl-nicotinic acid (CAS 1187930-16-0)
- 1-Benzyl-3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1430750-47-2)
- 924-41-4 C38864PH9K 1,5-Hexadien-3-ol Hexa-1,5-dien-3-ol AI3-28611 EINECS 213-102-7 UNII-C38864PH9K (CAS 924-41-4)
- 3-(Methylthio)-N-phenylaniline (CAS 13313-45-6)
- Neuropeptide GE (CAS 134748-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com