37418-88-5 3-Hydroxyphthalic anhydride Phthalic anhydride, 3-hydroxy- 5-18-03-00184 (Beilstein Handbook Reference) BRN 0135783 3-Hydroxyphthalic acid anhydride 1,3-Isobenzofurandione, 4-hydroxy- NSC 80858 CAS 37418-88-5

Purity 97%+In StockPharmaceutical Standards
CAS No.37418-88-5
Molecular FormulaC8H10O4
Molecular Weight170.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

37418-88-5 3-Hydroxyphthalic anhydride Phthalic anhydride, 3-hydroxy- 5-18-03-00184 (Beilstein Handbook Reference) BRN 0135783 3-Hydroxyphthalic acid anhydride 1,3-Isobenzofurandione, 4-hydroxy- NSC 80858 CAS 37418-88-5 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

37418-88-5 3-Hydroxyphthalic anhydride Phthalic anhydride, 3-hydroxy- 5-18-03-00184 (Beilstein Handbook Reference) BRN 0135783 3-Hydroxyphthalic acid anhydride 1,3-Isobenzofurandione, 4-hydroxy- NSC 80858 (CAS 37418-88-5), molecular formula C8H10O4 and molecular weight 170.16 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 37418-88-5 3-Hydroxyphthalic anhydride Phthalic anhydride, 3-hydroxy- 5-18-03-00184 (Beilstein Handbook Reference) BRN 0135783 3-Hydroxyphthalic acid anhydride 1,3-Isobenzofurandione, 4-hydroxy- NSC 80858 (C8H10O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 170.16 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H10O4
Molecular Weight170.16 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967

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