1-(Bromomethyl)-4,5-dichloro-2-methoxybenzene CAS 37420-52-3
| CAS No. | 37420-52-3 |
| Molecular Formula | C8H7BrCl2O |
| Molecular Weight | 269.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(Bromomethyl)-4,5-dichloro-2-methoxybenzene is closely related to a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(Bromomethyl)-4,5-dichloro-2-methoxybenzene (CAS 37420-52-3), molecular formula C8H7BrCl2O and molecular weight 269.95 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Bromomethyl)-4,5-dichloro-2-methoxybenzene (C8H7BrCl2O) is characterized by a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(Bromomethyl)-4,5-dichloro-2-methoxybenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7BrCl2O |
| Molecular Weight | 269.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl/Br-containing |
Related Bromomethyl Standards
- 1-(Bromomethyl)-3,4-dichloro-2-methoxybenzene (CAS 1936194-61-4)
- (αR)-α-(Bromomethyl)-2,4-dichlorobenzenemethanol (CAS 860439-01-6)
- 2,3-Bis(bromomethyl)thiophene (CAS 13250-86-7)
- 1-(bromomethyl)-2-nitro-4-(trifluoromethyl)benzene 162333-02-0 2-Nitro-4-(trifluoromethyl)benzyl bromide (CAS 162333-02-0)
- 1,4-Bis(bromomethyl)cyclohexane (CAS 35541-75-4)
- 1,2-Bis(bromomethyl)benzene 1,2-DIBENZYL BROMIDE 91-13-4 A,A'-DIBROMO-O-XYLENE A,A-DIBROMO-O-XYLENE ALPHA,ALPHA'-DIBROMO-2-XYLENE ALPHA,ALPHA'-DIBROMO-O-XYLENE ALPHA,ALPHA-DIBROMO-O-XYLENE AS00651 ATTERCOP-CHM AT113229 O-XYLIDENE DIBROMIDE O-XYLYLENE BROMIDE O-XYLYLENE DIBROMIDE SPEC-INF-BB S2183 (CAS 91-13-4)
- 3-Bromomethyl-6-methoxy-2-(trifluoromethyl)pyridine (CAS 1227496-52-7)
- 4-Bromomethyl-3-methoxy-2-(trifluoromethyl)pyridine (CAS 1227496-60-7)
Recommended Standards
- 1-(2-Bromoethoxy)-2,4-dichlorobenzene (CAS 6954-77-4)
- 1-Bromo-3,5-dichloro-4-(methoxymethyl)benzene (CAS 2121512-85-2)
- 2-(2-Bromoethoxy)-1,3-dichlorobenzene (CAS 26583-73-3)
- 2-(2-Bromoethoxy)-1,4-dichlorobenzene (CAS 85262-50-6)
- (3-(2-Methylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl)methanamine hydrochloride (CAS 1185294-93-2)
- ethyl 1-(2-aminoethyl)-3-piperidinecarboxylate (CAS 1221792-32-0)
- 2-Bromo-4-chloro-6-methylphenylisothiocyanate (CAS 1000571-58-3)
- 9-Bromo-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline (CAS 70173-54-5)
- 1-Cyclopropyl-1h-benzo[d]imidazole-4-carboxylic acid (CAS 1500022-28-5)
- 2-(4-(2-Chloro-6-fluorobenzyl)piperazin-1-yl)benzo[d]thiazole (CAS 478077-01-9)
- Sulfino-D-alanine (CAS 35554-99-5)
- 2-(Difluoromethyl)-5-methoxy-3-nitropyridine (CAS 1804689-11-9)
- (2,5-Dimethyl-1H-pyrrol-1-yl)acetic acid (CAS 109960-17-0)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com