Betahistine impurity 34 CAS 37445-98-0
| CAS No. | 37445-98-0 |
| Molecular Formula | C9H13NO3 |
| Molecular Weight | 183.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Betahistine impurity 34.
As a process- or degradation-related impurity, Betahistine impurity 34 (CAS 37445-98-0, C9H13NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Betahistine impurity 34 (C9H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 183.20 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Betahistine impurity 34 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H13NO3 |
| Molecular Weight | 183.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 1 |
Related Betahistine Standards
- Betahistine impurity 29 (CAS CATO-C4X-183829)
- Betahistine impurity 30 (CAS CATO-C4X-183830)
- Betahistine Impurity 46 (CAS 1903526-05-5)
- Betahistine impurity 28 (CAS CATO-C4X-183828)
- Betahistine impurity 40 (CAS CATO-C4X-183840)
- Betahistine Impurity 48 (CAS CATO-C4X-183848)
- Betahistine Impurity 18 (CAS 24028-46-4)
- Betahistine impurity 32 (CAS CATO-C4X-183832)
Recommended Standards
- Dipivefrine EP Impurity A (CAS 329-65-7)
- D-(+)-Epinephrine (CAS 150-05-0)
- Norepinephrine Impurity 17 (CAS CATO-C4X-151417)
- Adrenaline Impurity 23 (CAS 1894824-44-2)
- Trospium Impurity 14 (CAS CATO-C4X-203814)
- Oxacillin Impurity 32 (CAS CATO-C4X-232132)
- Calcipotriol Impurity 18 (CAS 2229745-37-1)
- 5-hydroxy-1,3-dihydrobenzimidazol-2-one (CAS 39513-24-1)
- H-D-Phe-L-Phe-D-Leu-D-Lys-L-Lys-γ-Pip-OH (CAS CATO-CPTD788744)
- 1-(Difluoromethyl)-3-methyl-1H-pyrazole-5-carboxylic acid (CAS 1006319-91-0)
- 2-(4,6-Bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-methoxyphenol (CAS 1820-28-6)
- 6-Amino-5-(4-chlorophenyl)-4-ethylpyrimidin-2(1H)-one trifluoroacetate salt (CAS 93456-61-2)
- N-((3-Methylisoxazol-5-yl)carbamothioyl)benzamide (CAS 118385-15-2)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com