H-Glu(His-OH)-OH CAS 37460-15-4

Purity >95%In StockPharmaceutical Standards
CAS No.37460-15-4
Molecular FormulaC11H16N4O5
Molecular Weight284.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

H-Glu(His-OH)-OH CAS 37460-15-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including H-Glu(His-OH)-OH.

CATO supplies H-Glu(His-OH)-OH (CAS 37460-15-4), a certified reference material (molecular formula C11H16N4O5, MW 284.27 g/mol) for analytical method development and quality control.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, H-Glu(His-OH)-OH is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), H-Glu(His-OH)-OH meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H16N4O5
Molecular Weight284.27 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967
Nitrogen Atoms4

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