p-Tolylisocyanate CAS 374675-64-6
| CAS No. | 374675-64-6 |
| Molecular Formula | C8H7NO |
| Molecular Weight | 133.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including p-Tolylisocyanate.
p-Tolylisocyanate (CAS 374675-64-6), molecular formula C8H7NO and molecular weight 133.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, p-Tolylisocyanate is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 133.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures p-Tolylisocyanate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7NO |
| Molecular Weight | 133.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Phenoxyacetonitrile (CAS 3598-14-9)
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- Zolpidem Impurity 17 (CAS 61960-32-5)
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- 1-(Cbz-amino)cyclopropanecarbonitrile (CAS 1159735-22-4)
- (4-((4-Chlorophenyl)amino)quinolin-3-yl)(thiomorpholino)methanone (CAS 1359177-31-3)
- 1-(3-Amino-5-bromopyridin-2-yl)ethanone hydrochloride (CAS 1986337-27-2)
- 6-Bromo-N-isopropylnicotinamide (CAS 1254123-86-8)
- 4-Nitrophenyl 2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-carboxylate (CAS 496854-73-0)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com