2-Chloro-N-(5-methoxypyrimidin-2-yl)acetamide CAS 374684-44-3
| CAS No. | 374684-44-3 |
| Molecular Formula | C7H8ClN3O2 |
| Molecular Weight | 201.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-N-(5-methoxypyrimidin-2-yl)acetamide (CAS 374684-44-3) is a high-purity analytical reference standard with the molecular formula C7H8ClN3O2 and a molecular weight of 201.61 g/mol.
Structurally, 2-Chloro-N-(5-methoxypyrimidin-2-yl)acetamide (C7H8ClN3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 201.61 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8ClN3O2 |
| Molecular Weight | 201.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 1-chloro-5-methoxy-2-methyl-4-nitrobenzene (CAS 100777-46-6)
- 1-Chloro-4-methoxy-2-methyl-5-nitrobenzene (CAS 101080-03-9)
- 1-Chloro-2-(methoxymethyl)-4-nitrobenzene (CAS 101513-52-4)
- 2-Chloro-4-(ethylamino)pyrimidine-5-carboxylic acid (CAS 101683-59-4)
- 3-Chloro-6-ethoxypyridine-2-carboxylic acid (CAS 1020945-92-9)
- 1-Chloro-2-ethoxy-4-nitrobenzene (CAS 102236-22-6)
- 2-(2-Chloro-6-nitrophenyl)ethan-1-ol (CAS 102493-68-5)
- 2-Chloro-N-(2,5-dihydroxy-phenyl)-acetamide (CAS 102580-34-7)
Recommended Standards
- 2-Chloro-N-(4-methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl)-acetamide (CAS 341010-69-3)
- 2-Chloro-N-ethyl-5-nitropyridin-4-amine (CAS 607373-89-7)
- 2-Chloro-6-methoxyisonicotinohydrazide (CAS 61832-07-3)
- 3-((6-Chloropyridazin-3-yl)amino)propanoic acid (CAS 27255-10-3)
- N-(1-Cyanocyclohexyl)-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 795293-42-4)
- 1-Isopropyl-2-methyl-4-nitro-1H-imidazole (CAS 35179-52-3)
- 1-[3-(azepan-1-ylmethyl)-4-hydroxyphenyl]ethan-1-one (CAS 923677-22-9)
- n-(2-(1h-Indol-3-yl)ethyl)-2-(2,4-dichlorophenoxy)acetamide (CAS 819807-03-9)
- Methyl 1-amino-3-(2-methyl-1h-imidazol-1-yl)cyclopentane-1-carboxylate (CAS 1522570-92-8)
- 1-((R)-Piperidin-3-yl)ethan-1-ol (CAS 2103039-66-1)
- 2-(2-Methylpyridin-4-yl)oxazole-4-carboxylic acid (CAS 1256786-78-3)
- N-((1-(Furan-3-carbonyl)piperidin-4-yl)methyl)isoxazole-5-carboxamide (CAS 1448046-03-4)
- 3-Bromo-1-methyl-1H-pyrazolo[3,4-c]pyridazine (CAS 2467610-87-1)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
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