7-Ethyl-8-(2-(2-hydroxybenzylidene)hydrazinyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione CAS 374767-63-2
| CAS No. | 374767-63-2 |
| Molecular Formula | C16H18N6O3 |
| Molecular Weight | 342.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Ethyl-8-(2-(2-hydroxybenzylidene)hydrazinyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CAS 374767-63-2) is a high-purity analytical reference standard with the molecular formula C16H18N6O3 and a molecular weight of 342.35 g/mol.
Structurally, 7-Ethyl-8-(2-(2-hydroxybenzylidene)hydrazinyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (C16H18N6O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 342.35 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Ethyl-8-(2-(2-hydroxybenzylidene)hydrazinyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H18N6O3 |
| Molecular Weight | 342.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 6 |
Related Ethyl Standards
- N'-(2-Hydroxybenzylidene)-3-(3-nitrophenyl)-1H-pyrazole-5-carbohydrazide (CAS 302918-07-6)
- 7-Ethyl-8-(2-(4-hydroxybenzylidene)hydrazinyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione (CAS 683790-67-2)
- 8-(2-(4-Hydroxybenzylidene)hydrazinyl)-1,3-dimethyl-7-(2-methylallyl)-3,7-dihydro-1H-purine-2,6-dione (CAS 361173-35-5)
- N'-(3-Hydroxybenzylidene)-5-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-3-carbohydrazide (CAS 303104-83-8)
- 4-((2-Hydroxybenzylidene)amino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one (CAS 30957-66-5)
- (Z)-2-(4-Hydroxybenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one (CAS 155099-32-4)
- 4-(4-Hydroxybenzylidene)-2-phenyloxazol-5(4H)-one (CAS 1226-71-7)
- N'-(2-Hydroxybenzylidene)-2-(4-methoxyphenoxy)acetohydrazide (CAS 328541-24-8)
Recommended Standards
- 7-Ethyl-2,3,6,7-tetrahydro-2,6-dioxo-3-(phenylmethyl)-1H-purine-1-acetic acid hydrazide (CAS 730949-89-0)
- Diethyl Azoxybenzene-4,4-dicarboxylate (CAS 34241-38-8)
- 6-Nitro-2,3-diphenylquinoxalin-5-amine (CAS 57436-93-8)
- Ethyl 2-imino-1-(2-methoxyethyl)-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate (CAS 371209-38-0)
- 2-((4-Methylquinazolin-2-yl)amino)quinazolin-4-ol (CAS 263746-95-8)
- 1-(2,5-Dichlorophenyl)-2,2,2-trifluoroethanone (CAS 886371-22-8)
- 3-(4-Methoxyphenyl)isothiazole-4-carboxylic acid (CAS 1239771-66-4)
- N-Fmoc-L-tyrosine Benzyl Ester (CAS 82911-77-1)
- 1-(5-amino-2-methylphenyl)-3,3-dimethylurea (CAS 1514414-40-4)
- DL-Valine-2,3-d2 (CAS 83181-79-7)
- (2S,3R,4S,5S)-5-(Hydroxymethyl)tetrahydrofuran-2,3,4-triol (CAS 40461-77-6)
- 2-Chloro-n-(1-cyanocycloheptyl)acetamide (CAS 78735-01-0)
- 1-(4-Chlorophenyl)-3-(dimethylamino)propan-1-one (CAS 2138-38-7)
- (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) (CAS 161650-01-7)
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