2-(piperazin-1-yl)acetic acidHCl CAS 37478-58-3
| CAS No. | 37478-58-3 |
| Molecular Formula | C6H12N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(piperazin-1-yl)acetic acidHCl is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(piperazin-1-yl)acetic acidHCl (CAS 37478-58-3), molecular formula C6H12N2O2H2O and molecular weight 162.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(piperazin-1-yl)acetic acidHCl (C6H12N2O2H2O) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H12N2O2 H2O |
| Molecular Weight | 162.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 2 |
Related piperazin Standards
- 2-(3-(Piperazin-1-yl)propyl)isoindoline-1,3-dione (CAS 1000547-80-7)
- (4-Methyl-piperazin-1-yl)-(S)-pyrrolidin-2-yl-methanone (CAS 100158-68-7)
- (6-(Piperazin-1-yl)pyridin-3-yl)boronic acid (CAS 1003043-67-1)
- (2-(Piperazin-1-yl)pyridin-4-yl)boronic acid (CAS 1003043-70-6)
- N-(4-(Piperazin-1-ylsulfonyl)phenyl)acetamide (CAS 100318-71-6)
- Piperazin-1-yl(m-tolyl)methanone hydrochloride (CAS 100940-01-0)
- 2-(Piperazin-1-yl)phenol (CAS 1011-17-2)
- 2-phenyl-1-(piperazin-1-yl)butan-1-one (CAS 1016503-45-9)
Recommended Standards
- 4-((3-(Trifluoromethyl)pyridin-2-yl)oxy)benzaldehyde (CAS 1086379-05-6)
- 4,7-dichloro-1H-1,3-benzimidazole (CAS 21295-91-0)
- (2E)-2-Cyano-3-(dimethylamino)-N'-[(3E)-6,6,6-trifluoro-5-oxohexan-3-ylidene]prop-2-enehydrazide (CAS 478063-93-3)
- 4-Iodoisoxazol-3-amine (CAS 1500614-87-8)
- 4,4,5,5-Tetramethyl-2-(2-(methylthio)-5-nitrophenyl)-1,3,2-dioxaborolane (CAS 2377610-39-2)
- (E)-4-(2-(methylsulfonyl)vinyl)isoquinoline (CAS 918341-20-5)
- (4aR,7aR)-tert-Butyl octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate (CAS 186201-89-8)
- 7-Methoxy-7-oxoheptanoic Acid (CAS 20291-40-1)
- 2-(tert-Butyl)-4-(1-methylcyclopropyl)-6-(piperazin-1-yl)pyrimidine (CAS 876028-69-2)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
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