(R)-4,4,4-Trifluoro-3-phenylbutanoic acid CAS 374782-31-7

Description

The molecular framework of (R)-4,4,4-Trifluoro-3-phenylbutanoic acid (C10H9F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO supplies (R)-4,4,4-Trifluoro-3-phenylbutanoic acid (CAS 374782-31-7), a certified reference material (molecular formula C10H9F3O2, MW 218.17 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-4,4,4-Trifluoro-3-phenylbutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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