2-Chloro-5-(pyridin-2-yl)pyrimidine CAS 374927-80-7
| CAS No. | 374927-80-7 |
| Molecular Formula | C9H6ClN3 |
| Molecular Weight | 191.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-5-(pyridin-2-yl)pyrimidine (CAS 374927-80-7), molecular formula C9H6ClN3 and molecular weight 191.62 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-5-(pyridin-2-yl)pyrimidine (C9H6ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-5-(pyridin-2-yl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6ClN3 |
| Molecular Weight | 191.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-1-methyl-1H-indazole-3-carbonitrile (CAS 1015846-56-6)
- 2-Chloro-5-(pyridin-4-yl)pyrimidine (CAS 1211522-15-4)
- 2-Chloro-5-(pyridin-3-yl)pyrimidine (CAS 1211588-38-3)
- 2-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-1-yl)acetonitrile (CAS 1246744-46-6)
- 5-Chloro-6-cyano-2-methyl-7-azaindole (CAS 1352396-10-1)
- 2-Chloro-3-(pyridin-4-yl)pyrazine (CAS 1480200-22-3)
- 2-{4-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}acetonitrile (CAS 1553024-32-0)
- 4-Chloro-5-(pyridin-4-yl)pyrimidine (CAS 1598739-19-5)
Recommended Standards
- 2-Chloro-4-phenyl-1,3,5-triazine (CAS 77007-96-6)
- 3-Chloro-1-methyl-1H-indazole-4-carbonitrile (CAS 256228-71-4)
- 2-Chloro-4-(3-pyridyl)pyrimidine (CAS 483324-01-2)
- 3-Chloro-6-(pyridin-2-yl)pyridazine (CAS 78784-70-0)
- N1-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-N1-isopropylethane-1,2-diamine (CAS 1353986-10-3)
- Pyrvinium chloride (CAS 548-84-5)
- 4-Hydroxy-2-methyl-1,4-dihydropyrimidine-5-carboxylic acid (CAS 157335-90-5)
- 5-Amino-4-methoxybenzofuran-6-ol (CAS 105849-73-8)
- (S)-1-(4-fluorophenyl)-2,2-dimethylpropan-1-amine (CAS 1389862-91-2)
- (3S,4R)-1-(tert-butoxycarbonyl)-3-phenylpiperidine-4-carboxylic acid (CAS 951742-83-9)
- (4-(N-Cyclopentylsulfamoyl)-3-fluorophenyl)boronic acid (CAS 1704120-92-2)
- 3-Phenyl-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylic acid (CAS 1082193-69-8)
- 2-(Hexadecyloxy)benzoic acid (CAS 5377-19-5)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com