2-((Chloromethyl)thio)-1H-benzo[d]imidazole CAS 37525-49-8
| CAS No. | 37525-49-8 |
| Molecular Formula | C8H7ClN2S |
| Molecular Weight | 198.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-((Chloromethyl)thio)-1H-benzo[d]imidazole (CAS 37525-49-8), a certified reference material (molecular formula C8H7ClN2S, MW 198.67 g/mol) for analytical method development and quality control.
2-((Chloromethyl)thio)-1H-benzo[d]imidazole (C8H7ClN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2S |
| Molecular Weight | 198.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
- Methyl 4-(chloromethyl)-2-methylbenzoate (CAS 1174046-29-7)
- 2-(Chloromethyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one (CAS 145475-35-0)
- 1-[5-(Chloromethyl)-2-methoxyphenyl]ethan-1-one (CAS 87604-20-4)
- 3-(4-(Chloromethyl)phenyl)propanoic acid (CAS 56703-33-4)
- 4-(Chloromethyl)-2,5-dimethylbenzoic acid (CAS 863914-07-2)
- 4-(Chloromethyl)-2-phenyl-1,3-dioxolane, mixture of diastereomers (CAS 36236-72-3)
- 7-(Chloromethyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepine (CAS 67869-70-9)
- Ethyl 3-(chloromethyl)benzoate (CAS 54589-54-7)
Recommended Standards
- 1-(Methoxymethyl)cyclobutane-1-sulfonyl chloride (CAS 2138278-39-2)
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- 1-(2-Methoxyethyl)cyclopropane-1-sulfonyl chloride (CAS 2001834-79-1)
- 2-Chloro-4-methyl-6-(methylthio)nicotinonitrile (CAS 51564-48-8)
- 3-Bromo-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine (CAS 138023-17-3)
- 6,7-Dimethoxy-1,2,3,4-tetrahydroquinoline (CAS 99986-04-6)
- (2,4,6-Trimethylphenyl)methanamine hydrochloride (CAS 202522-00-7)
- N-(2-Fluorobenzyl)-2-(pyrazine-2-carboxamido)oxazole-4-carboxamide (CAS 1396886-72-8)
- (S)-Methyl 4-oxotetrahydrofuran-3-carboxylate (CAS 2198170-24-8)
- Labdanolic acid (CAS 10267-24-0)
- 3-Bromo-4-(3,3-difluoroazetidin-1-yl)benzonitrile (CAS 1774896-20-6)
- 1-(2-Chlorophenyl)-3-(4-methoxyphenyl)propan-1-one (CAS 898775-98-9)
- D-erythro-Sphingosine-N-tert-butyloxycarbonyl-O-tert-butyldimethylsilyl (CAS 342655-72-5)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com