5-(2-Hydroxyphenyl)-2,3-dihydro-1H-1,2,4-triazole-3-thione CAS 37536-29-1
| CAS No. | 37536-29-1 |
| Molecular Formula | C8H7N3OS |
| Molecular Weight | 193.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(2-Hydroxyphenyl)-2,3-dihydro-1H-1,2,4-triazole-3-thione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(2-Hydroxyphenyl)-2,3-dihydro-1H-1,2,4-triazole-3-thione (CAS 37536-29-1), molecular formula C8H7N3OS and molecular weight 193.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(2-Hydroxyphenyl)-2,3-dihydro-1H-1,2,4-triazole-3-thione (C8H7N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(2-Hydroxyphenyl)-2,3-dihydro-1H-1,2,4-triazole-3-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7N3OS |
| Molecular Weight | 193.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Hydroxyphenyl Standards
- 1-(2-Hydroxyphenyl)-2-thiocyanatoethan-1-one (CAS 98589-48-1)
- N-(4-Hydroxyphenyl)-N,2-Dimethylpropanamide (CAS 1042580-33-5)
- 2-(3-Hydroxyphenyl)-N-propylacetamide (CAS 1249044-75-4)
- 4-(4-Hydroxyphenyl)piperidin-4-ol (CAS 142001-84-1)
- 1-(4-Hydroxyphenyl)piperidin-4-ol (CAS 866109-91-3)
- 4-(2-Hydroxyphenyl)piperidin-4-ol (CAS 336882-80-5)
- N-(2-Hydroxyphenyl)pivalamide (CAS 64414-11-5)
- N-(3-hydroxyphenyl)pentanamide (CAS 55791-89-4)
Recommended Standards
- 5-(2-Aminophenyl)-1,3,4-oxadiazole-2(3H)-thione (CAS 32058-76-7)
- 5-(4-Aminophenyl)-1,3,4-oxadiazole-2-thiol (CAS 32058-82-5)
- 4-Methyl-5-(pyrazin-2-yl)-4h-1,2,4-triazole-3-thiol (CAS 219600-07-4)
- 5-[2-(furan-2-yl)ethenyl]-1,3,4-thiadiazol-2-amine (CAS 299935-03-8)
- 2-(Quinolin-4-yloxy)ethan-1-ol (CAS 24220-96-0)
- 2-(2-Hydroxy-3-(phenylsulfonyl)propoxy)benzonitrile (CAS 478079-74-2)
- Ethyl 2-Acetamido-2-ethoxycarbonyl-3-(2-ethyl-5-methyl-3-oxoisoxazolin-4-yl) propionate (CAS 127020-33-1)
- 2-Hydroxy-1,4-Naphthoquinone (CAS 83-72-7)
- 2-Acetyl-N,N-dibutylpent-4-enamide (CAS 397286-41-8)
- 1-(2-Fluorocyclopenten-1-yl)ethanone (CAS 2301859-83-4)
- BLZ945 (CAS 953769-46-5)
- N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-ethylbenzo[d][1,3]dioxole-5-carboxamide (CAS 898413-32-6)
- Dapagliflozin Impurity 90 (CAS 29643-62-7)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
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