5-Methylpyrazine-2-carbohydrazide CAS 37545-33-8
| CAS No. | 37545-33-8 |
| Molecular Formula | C6H8N4O |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Methylpyrazine-2-carbohydrazide.
5-Methylpyrazine-2-carbohydrazide (CAS 37545-33-8), molecular formula C6H8N4O and molecular weight 152.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Methylpyrazine-2-carbohydrazide (C6H8N4O) is characterized by an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Methylpyrazine-2-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8N4O |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 4 |
Related Methylpyrazine Standards
- 3-Methylpyrazine-2-carbohydrazide (CAS 104893-68-7)
- 6-Methylpyrazine-2-carbohydrazide (CAS 105426-65-1)
- Methyl 3-Methylpyrazine-2-carboxylate (CAS 41110-29-6)
- Methyl 6-Methylpyrazine-2-carboxylate (CAS 41110-38-7)
- N'-Methylpyrazine-2-carbohydrazide (CAS 80364-57-4)
- N-Methylpyrazine-2-carbohydrazide (CAS 80364-49-4)
- (5-Methylpyrazine-2,3-diyl)dimethanamine (CAS 771581-05-6)
- N'-Methylpyrazine-2-carbohydrazonamide (CAS 299465-06-8)
Recommended Standards
- 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 85614-92-2)
- 5-Methylpyrimidine-2-carbohydrazide (CAS 87362-27-4)
- 5-Methoxypicolinamide (CAS 88166-65-8)
- 5-Oxotricyclo[2.2.1.0,2,6]heptane-3-carboxylic acid (CAS 70748-53-7)
- Columbianadin (CAS 5058-13-9)
- (3-(Azetidin-1-ylmethyl)phenyl)(2,4-dichlorophenyl)methanone (CAS 898772-09-3)
- 1-benzyl-5-methylpiperidin-3-amine (CAS 1315367-65-7)
- Decyl 2-cyanoacrylate (CAS 3578-07-2)
- 3-(4-methylpiperazin-1-yl)oxolane-3-carboxylic acid dihydrochloride (CAS 2060041-56-5)
- 2-[2-(2,6-Dichloro-4-hydroxphenylamino)phenyl-d (CAS 1382084-40-3)
- N-(5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)propan-2-amine (CAS 2096336-54-6)
- 4-Methyl-N-(thiophen-3-ylmethyl)pyridin-3-amine (CAS 1340521-62-1)
- 8-(2,6-Difluorophenyl)-8-oxooctanoic acid (CAS 898766-52-4)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com