4-(Piperidin-4-ylmethyl)aniline CAS 37581-35-4

Purity 97%+In StockPharmaceutical Standards
CAS No.37581-35-4
Molecular FormulaC12H18N2
Molecular Weight190.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Piperidin-4-ylmethyl)aniline CAS 37581-35-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 190.28 g/mol gives 4-(Piperidin-4-ylmethyl)aniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(Piperidin-4-ylmethyl)aniline (CAS 37581-35-4) is a high-purity analytical reference standard with the molecular formula C12H18N2 and a molecular weight of 190.28 g/mol.

The molecular framework of 4-(Piperidin-4-ylmethyl)aniline (C12H18N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Piperidin-4-ylmethyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H18N2
Molecular Weight190.28 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967
Nitrogen Atoms2

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