2-Chloro-1-(6-methoxy-2,2,4-trimethylquinolin-1(2H)-yl)ethan-1-one CAS 375833-63-9
| CAS No. | 375833-63-9 |
| Molecular Formula | C15H18ClNO2 |
| Molecular Weight | 279.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 279.76 g/mol gives 2-Chloro-1-(6-methoxy-2,2,4-trimethylquinolin-1(2H)-yl)ethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-1-(6-methoxy-2,2,4-trimethylquinolin-1(2H)-yl)ethan-1-one (CAS 375833-63-9), molecular formula C15H18ClNO2 and molecular weight 279.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-1-(6-methoxy-2,2,4-trimethylquinolin-1(2H)-yl)ethan-1-one (C15H18ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-1-(6-methoxy-2,2,4-trimethylquinolin-1(2H)-yl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H18ClNO2 |
| Molecular Weight | 279.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 1-(Tert-butyl)-6-(4-chlorophenyl)piperidine-2,4-dione (CAS 400079-95-0)
- 1-(4-Chlorophenethyl)-5-methoxy-3,4-dimethyl-1,5-dihydro-2H-pyrrol-2-one (CAS 731831-70-2)
- 4-(Chlorodiphenylmethyl)pyridine (CAS 42362-54-9)
- 1-(3-Chloropropyl)-8-methoxy-3,6-dimethylquinolin-2(1H)-one (CAS 2113977-72-1)
- 1,1-Diphenyl-4-(1H-1,2,4-triazol-1-yl)but-2-yn-1-ol (CAS 209970-11-6)
- (1R,2S)-2-(3,4-dichlorobenzoyl)cyclohexane-1-carboxylic acid (CAS 844856-66-2)
- 1-(2-Bromo-6-(trifluoromethyl)phenyl)-4,4-difluoropiperidine (CAS 1779122-85-8)
- 4-Amino-3-bromo-5-chloro-2-methylpyridine, 97% (CAS 1247348-53-3)
- 2,6-Dimethoxy-N-(3-(pentan-3-yl)isoxazol-5-yl)benzamide (CAS 82558-72-3)
- (R)-N-(1-(4-formylphenyl)ethyl)methanesulfonamide (CAS 1448682-03-8)
- ((((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)phosphonic acid (CAS 77032-40-7)
- (S)-4-chloro-1,2-epoxybutane (CAS 13067-79-3)
- Brexpiprazole impurity 115 (CAS CATO-C4X-1131115)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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