Fluvastatin Alcohol Ketone CAS 375846-25-6
| CAS No. | 375846-25-6 |
| Molecular Formula | C28H32FNO4 |
| Molecular Weight | 465.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Fluvastatin Alcohol Ketone (CAS 375846-25-6), molecular formula C28H32FNO4 and molecular weight 465.56 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Fluvastatin Alcohol Ketone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 465.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H32FNO4 |
| Molecular Weight | 465.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluvastatin Standards
- Fluvastatin EP Impurity B (CAS 194934-96-8)
- Fluvastatin Impurity N1 (CAS 194935-00-7)
- Fluvastatin Methyl Ester (CAS 93957-53-0)
- Fluvastatin EP Impurity C(Sodium Salt) (CAS 2451176-31-9 (free acid))
- Fluvastatin Sodium - Impurity A (CAS 1025085-49-7)
- Fluvastatin Impurity 16 (CAS 2117644-62-7)
- Fluvastatin EP Impurity D (CAS 1160169-39-0)
- Fluvastatin EP Impurity C (CAS 2451176-31-9)
Recommended Standards
- L702958 (CAS 136079-88-4)
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- 2,2-Dimethyl-4-phenylbutan-1-ol (CAS 15732-85-1)
- Lixisenatide (CAS 320367-13-3（free base）)
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