5-Chloro-1,2-diphenyl-4-(piperidin-1-ylmethyl)-1H-pyrazol-3(2H)-one CAS 37585-42-5
| CAS No. | 37585-42-5 |
| Molecular Formula | C21H22ClN3O |
| Molecular Weight | 367.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Chloro-1,2-diphenyl-4-(piperidin-1-ylmethyl)-1H-pyrazol-3(2H)-one (C21H22ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-Chloro-1,2-diphenyl-4-(piperidin-1-ylmethyl)-1H-pyrazol-3(2H)-one (CAS 37585-42-5), molecular formula C21H22ClN3O and molecular weight 367.87 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H22ClN3O |
| Molecular Weight | 367.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 3-Iodo-4-isobutylbenzoic acid (CAS 1131588-08-3)
- 1-(2-Chlorophenyl)hexan-2-one (CAS 1177241-40-5)
- 3-(2H-tetrazol-2-yl)adamantan-1-amine (CAS 915922-22-4)
- rac-(1R,3S)-3-methoxy-2,2-dimethylcyclobutan-1-ol (CAS 1909288-29-4)
- (S)-2-(3-chloro-5-methylphenyl)pyrrolidine (CAS 1213444-42-8)
- Methyl 2-bromo-3-chloro-6-fluorobenzoate (CAS 1805210-84-7)
- N-[3-(3-Pyrrolidinyloxy)phenyl]acetamidehydrochloride (CAS 1220033-74-8)
- Methyl 2-(benzo[d][1,3]dioxole-5-carboxamido)benzoate (CAS 67848-13-9)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
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