4-(Piperidin-4-ylmethyl)aniline dihydrochloride CAS 37586-21-3
| CAS No. | 37586-21-3 |
| Molecular Formula | C12H18N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(Piperidin-4-ylmethyl)aniline dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(Piperidin-4-ylmethyl)aniline dihydrochloride (CAS 37586-21-3) is a high-purity analytical reference standard with the molecular formula C12H18N2HCl and a molecular weight of 226.75 g/mol.
The molecular framework of 4-(Piperidin-4-ylmethyl)aniline dihydrochloride (C12H18N2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H18N2 2*HCl |
| Molecular Weight | 226.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Piperidin Standards
- 1000339-76-3 Ethyl 2-(Piperidin-1-yl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ethyl 2-(piperidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate ethyl 2-piperidin-1-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate (CAS 1000339-76-3)
- 2-(Piperidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 1000339-77-4)
- Benzyl 2-(piperidin-4-yl)acetate hydrochloride (CAS 1000872-47-8)
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- 1000958-55-3 4-Ethyl-1-[2-(piperidin-4-yl)ethyl]piperidine DTXSID60649257 (CAS 1000958-55-3)
- 5-(Piperidin-2-yl)pyridin-2-amine (CAS 100133-12-8)
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Recommended Standards
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- 2-(3,4-Dimethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160264-86-7)
- 2, 5, 7- Trimethyl-3H- imidazo[4, 5- b] pyridine (CAS 158229-19-7)
- n-Cyclopropyl-4-ethylcyclohexan-1-amine hydrochloride (CAS 1177316-81-2)
- Methyl 2-(oxazol-5-yl)acetate (CAS 947771-08-6)
- 2-Chloro-3-iodo-4,5,6-trimethylpyridine (CAS 2140326-91-4)
- Ropivacaine EP Impurity D (R-Isomer) (CAS 98626-60-9)
- 5-Bromo-1-cyclopropyl-1H-benzo[d]imidazole (CAS 1368759-44-7)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
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