(2e)-3-(4-Methoxyphenyl)but-2-enoic acid CAS 376346-53-1
| CAS No. | 376346-53-1 |
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2e)-3-(4-Methoxyphenyl)but-2-enoic acid (C11H12O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(2e)-3-(4-Methoxyphenyl)but-2-enoic acid (CAS 376346-53-1) is a high-purity analytical reference standard with the molecular formula C11H12O3 and a molecular weight of 192.21 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2e)-3-(4-Methoxyphenyl)but-2-enoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related e Standards
- trans-2-(2-Methoxyphenyl)cyclopropanecarboxylic Acid (CAS 110826-01-2)
- 1-(4-Methoxyphenyl)butane-2,3-dione (CAS 1213223-28-9)
- (E)-4-(2-methoxyphenyl)but-3-enoic acid (CAS 127404-71-1)
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Recommended Standards
- (2E)-3-(2-Methoxy-4-methylphenyl)prop-2-enoic acid (CAS 53005-58-6)
- (2e)-3-[5-(2-methylcyclopropyl)furan-2-yl]prop-2-enoic acid (CAS 875159-65-2)
- (2-(3,6-Dihydro-2H-pyran-4-yl)pyrimidin-4-yl)methanol (CAS 2287219-02-5)
- (2-Methyl-2,3-dihydro-benzofuran-5-yl)-acetic acid (CAS 889939-89-3)
- 1-Biphenyl-3-yl-ethylamine (CAS 110826-97-6)
- Perfluorophenyl acetate (CAS 19220-93-0)
- N1,N5,N10-Tri-p-coumaroylspermidine (CAS 131086-78-7)
- Dimethyl 2',5'-diethoxy-[1,1':4',1''-terphenyl]-4,4''-dicarboxylate (CAS 1802676-78-3)
- 3-(2,6-Bis(trifluoromethyl)phenyl)pyridine (CAS 1214333-44-4)
- Cefalexin Impurity 30 (CAS 65870-51-1)
- 1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl α-methylbenzeneacetate (CAS 2092571-50-9)
- (1S,2S)-2-aminocyclopentane-1-carboxamide (CAS 900518-33-4)
- N1-cyclohexyl-N1-methyl-4-(methylsulfonyl)benzene-1,3-diamine (CAS 1220033-81-7)
- Endo-Gly29-Tirzepatide (CAS CATO-CPTD788685)
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