4-[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzoic acid CAS 376372-41-7
| CAS No. | 376372-41-7 |
| Molecular Formula | C13H13BrN2O2 |
| Molecular Weight | 309.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzoic acid.
CATO supplies 4-[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzoic acid (CAS 376372-41-7), a certified reference material (molecular formula C13H13BrN2O2, MW 309.16 g/mol) for analytical method development and quality control.
4-[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzoic acid (C13H13BrN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13BrN2O2 |
| Molecular Weight | 309.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
- n-(3-Bromo-4-methylphenyl)-3-(1h-1,2,3-triazol-1-yl)propanamide (CAS 1031064-47-7)
- Ethyl 4-bromo-5-methyl-1-phenylpyrazole-3-carboxylate (CAS 1171535-98-0)
- 4-bromo-N-[(4-hydroxyphenyl)methyl]-N-methyl-1H-pyrrole-2-carboxamide (CAS 1183454-77-4)
- 4-Bromo-n-[(2-hydroxyphenyl)methyl]-n-methyl-1h-pyrrole-2-carboxamide (CAS 1184212-09-6)
- 1-(4-Bromo-benzyl)-1H-pyrazole-4-carboxylic acid ethyl ester (CAS 1197232-22-6)
- 1-(3-Bromo-benzyl)-1H-pyrazole-4-carboxylic acid ethyl ester (CAS 1197233-82-1)
- Ethyl 6-bromo-4-(methylamino)quinoline-3-carboxylate (CAS 1216486-66-6)
- 5-Bromo-N-methyl-N-((1-methyl-1h-pyrazol-4-yl)methyl)nicotinamide (CAS 1241255-12-8)
Recommended Standards
- 4-(4-Bromophenyl)-1-methyl-1H-imidazole-2-carboxylic acid ethyl ester (CAS 869568-12-7)
- 4-Bromo-3,5-dimethyl-2-(4-nitrobenzyl)-2H-pyrrole (CAS 937602-06-7)
- 4-(3-(4-Bromophenyl)acryloyl)piperazin-2-one (CAS 851298-02-7)
- 4-Bromo-5-ethoxy-2-(p-tolyl)pyridazin-3(2H)-one (CAS 400088-47-3)
- (5-Fluoro-3-methyl-1H-indol-2-yl)methanol (CAS 706789-01-7)
- 1-((Tetrahydrofuran-2-yl)methyl)-1H-pyrazole-4-carboxylic acid (CAS 1248774-64-2)
- 2-Bromoacridine-9-carbonitrile (CAS 958452-37-4)
- 4-Acetamido-2-methylbenzene-1-sulfonyl chloride (CAS 62374-67-8)
- 3-Bromo-N-(pyridin-3-yl)benzamide (CAS 349405-43-2)
- m-Carboxycinnamic acid bishydroxamide (CAS 174664-65-4)
- n-(4-Morpholinophenyl)-3-(trifluoromethyl)benzamide (CAS 250714-44-4)
- 2-(5-Bromo-2-methylphenyl)-5-methyl-1,3,4-oxadiazole (CAS 1267418-52-9)
- Ethyl 3,4-dihydroxy-2-methylbenzoate (CAS 217190-34-6)
- Immunstimulating Peptide, human (CAS 94773-24-7)
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