1-Nitro-4-(2,2,2-trifluoroethyl)benzene CAS 3764-36-1
| CAS No. | 3764-36-1 |
| Molecular Formula | C8H6F3NO2 |
| Molecular Weight | 205.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Nitro-4-(2,2,2-trifluoroethyl)benzene (C8H6F3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-Nitro-4-(2,2,2-trifluoroethyl)benzene (CAS 3764-36-1) is a high-purity analytical reference standard with the molecular formula C8H6F3NO2 and a molecular weight of 205.13 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-Nitro-4-(2,2,2-trifluoroethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F3NO2 |
| Molecular Weight | 205.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nitro Standards
- 1-Methyl-3-nitro-2-(trifluoromethyl)benzene (CAS 112641-21-1)
- 1-Nitro-3-(2,2,2-trifluoroethyl)benzene (CAS 114980-30-2)
- 1-Nitro-2-(2,2,2-trifluoroethyl)benzene (CAS 145914-06-3)
- 4-Methyl-2-nitro-1-(trifluoromethyl)benzene (CAS 154057-13-3)
- 1960-52-7 2-METHYL-4-NITRO-1-(TRIFLUOROMETHYL)BENZENE 2-Methyl-4-nitrobenzotrifluoride 3-AMINO-4-(TRIFLUOROMETHYLTHIO)TOLUENE 5-NITRO-2-(TRIFLUOROMETHYL)TOLUENE AS05935 BENZENE, 2-METHYL-4-NITRO-1-(TRIFLUOROMETHYL)- (CAS 1960-52-7)
- 1-Methyl-2-nitro-3-(trifluoromethyl)benzene (CAS 92891-23-1)
- 1-Methyl-2-nitro-4-(trifluoromethyl)benzene (CAS 65754-26-9)
- 1-Methyl-3-nitro-5-(trifluoromethyl)benzene (CAS 96783-80-1)
Recommended Standards
- 1-Methyl-4-(2,2,2-trifluoroacetyl)-1H-pyrrole-2-carbaldehyde (CAS 482584-40-7)
- 2-(1,1-Difluoroethyl)-1-fluoro-4-nitrobenzene (CAS 445303-19-5)
- 2-(2,2,2-Trifluoroethoxy)nicotinaldehyde (CAS 902837-51-8)
- 2-(5-(Trifluoromethyl)pyridin-2-yl)acetic acid (CAS 785762-99-4)
- 3-Bromo-2-methyl-7-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 439107-63-8)
- 2,3,6,7-Tetramethyl Anthracene (CAS 15254-25-8)
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- 5-Amino-1-(4-methoxy-2-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1416344-73-4)
- N-(2,6-Dimethylphenyl)piperazine-2-carboxamide dihydrochloride (CAS 36385-60-1)
- 2-(Aminomethyl)-5-(difluoromethyl)-4-fluoro-3-methoxypyridine (CAS 1805048-57-0)
- (R)-2-Chloro-5,6,7,8-tetrahydroquinolin-8-ol (CAS 1239880-26-2)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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