5-Iodo-2-(trifluoromethyl)-1H-benzo[d]imidazole CAS 3765-86-4

Purity 97%+In StockPharmaceutical Standards
CAS No.3765-86-4
Molecular FormulaC8H4F3IN2
Molecular Weight312.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Iodo-2-(trifluoromethyl)-1H-benzo[d]imidazole CAS 3765-86-4 chemical structure

Description

The occurrence of 5-Iodo-2-(trifluoromethyl)-1H-benzo[d]imidazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Iodo-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 3765-86-4), molecular formula C8H4F3IN2 and molecular weight 312.03 g/mol, is a CATO reference standard with documented purity and traceability.

5-Iodo-2-(trifluoromethyl)-1H-benzo[d]imidazole (C8H4F3IN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-Iodo-2-(trifluoromethyl)-1H-benzo[d]imidazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H4F3IN2
Molecular Weight312.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Halogen ContentF/I-containing
Nitrogen Atoms2

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