4-(2,4-Difluorophenyl)-3-methyl-2(5H)-furanone CAS 376584-79-1
| CAS No. | 376584-79-1 |
| Molecular Formula | C11H8F2O2 |
| Molecular Weight | 210.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2,4-Difluorophenyl)-3-methyl-2(5H)-furanone (CAS 376584-79-1) is a high-purity analytical reference standard with the molecular formula C11H8F2O2 and a molecular weight of 210.18 g/mol.
The molecular framework of 4-(2,4-Difluorophenyl)-3-methyl-2(5H)-furanone (C11H8F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2,4-Difluorophenyl)-3-methyl-2(5H)-furanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8F2O2 |
| Molecular Weight | 210.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Difluorophenyl Standards
- 2-(3,4-Difluorophenyl)-5-ethyl-1,3,4-oxadiazole (CAS 1171930-47-4)
- (5-(2,6-Difluorophenyl)furan-2-yl)methanol (CAS 1178841-28-5)
- 1-(3,4-Difluorophenyl)-5-methyl-2,3-dihydro-1h-imidazol-2-one (CAS 1197906-25-4)
- Ethyl 3-(3,4-difluorophenyl)propiolate (CAS 1229236-35-4)
- (3,4-Difluorophenyl)(furan-3-yl)methanol (CAS 1247414-90-9)
- (3,4-Difluorophenyl)(furan-2-yl)methanol (CAS 1247705-38-9)
- (1-(3,4-Difluorophenyl)-1H-1,2,3-triazol-4-yl)methanamine (CAS 1248914-98-8)
- (1-(2,3-Difluorophenyl)-1H-1,2,3-triazol-4-yl)methanamine (CAS 1249833-86-0)
Recommended Standards
- 3-Methoxy-5-(methoxycarbonyl)benzoic Acid (CAS 71590-08-4)
- 4-(2-Methoxy-2-oxoethoxy)benzoic acid (CAS 63787-32-6)
- 3-Methoxy-4-methylphthalic acid (CAS 861555-37-5)
- 4,4-Difluoro-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one (CAS 56875-01-5)
- (2-Chloro-4-fluorobenzyl)(methyl)sulfane (CAS 1443326-63-3)
- 3-azanylidene-6-(chloromethyl)-4-oxidanyl-pyrazine-2-carbonitrile 40127-89-7 6-(chloromethyl)-4-hydroxy-3-imino-2-pyrazinecarbonitrile A824925 (CAS 40127-89-7)
- 2-(4-(Benzyloxy)-3-ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1257078-56-0)
- Thiazolylmethyl-4-nitrophenylcarbonate-13C3 (CAS 1189969-30-9)
- 1,2,4,5,6,7,8,8A-octahydroazulen-2-one (CAS 61154-46-9)
- 4-Benzoyl-1-[(2-chloro-6-fluorophenyl)methyl]-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317822-18-7)
- (1-Ethynylcyclobutyl)methanol (CAS 2090582-79-7)
- α-[2-(2,4-Difluorophenyl)-2-oxoethyl]-1H-indole-3-acetic Acid (CAS 1354707-41-7)
- Methyl 3-(m-tolyl)propiolate (CAS 7515-23-3)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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