2-Methyl-4-(trifluoromethoxy)benzenesulfonyl chloride CAS 376637-84-2
| CAS No. | 376637-84-2 |
| Molecular Formula | C8H6ClF3O3S |
| Molecular Weight | 274.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Methyl-4-(trifluoromethoxy)benzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Methyl-4-(trifluoromethoxy)benzenesulfonyl chloride (CAS 376637-84-2), a certified reference material (molecular formula C8H6ClF3O3S, MW 274.64 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Methyl-4-(trifluoromethoxy)benzenesulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O3S |
| Molecular Weight | 274.64 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Methyl Standards
- (2-(Trifluoromethoxy)phenyl)methanesulfonyl chloride (CAS 116827-38-4)
- 5-Methyl-2-(trifluoromethoxy)benzenesulfonyl chloride (CAS 1261683-44-6)
- 2-Methyl-5-(trifluoromethoxy)benzenesulfonyl chloride (CAS 1261852-46-3)
- (3-(Trifluoromethoxy)phenyl)methanesulfonyl chloride (CAS 1263274-68-5)
- 4-(Trifluoromethoxy)phenylmethanesulfonyl chloride (CAS 683813-55-0)
- 1-{[4-(Trifluoromethoxy)phenyl]methyl}-1,4-diazepane (CAS 1016704-67-8)
- 2-Methyl-1-{[4-(trifluoromethoxy)phenyl]methyl}piperazine (CAS 1240581-54-7)
- 1-(4-(Trifluoromethoxy)benzyl)piperidin-4-amine (CAS 1279219-09-8)
Recommended Standards
- 2-Methoxy-5-(trifluoromethyl)benzenesulfonyl chloride (CAS 612541-12-5)
- 4-(2,2,2-Trifluoroethoxy)benzene-1-sulfonyl chloride (CAS 954369-08-5)
- 2,2,2-Trifluoroethyl 4-chlorobenzenesulfonate (CAS 85459-26-3)
- [2-Fluoro-(4-difluoromethoxy)phenyl]-methanesulfonyl chloride (CAS 1987007-08-8)
- Malachite Green Oxalate (CAS 18015-76-4)
- 2-(4-Fluorophenyl)-1-(2-((3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)amino)-6,7-dihydrothiazolo[5,4-c]pyridin-5(4H)-yl)ethanone (CAS 1077629-25-4)
- (r)-2-Amino-2-(3-chloro-4-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1213466-53-5)
- tert-Butyl 2-methyl-3-oxo-1,2,3,4,5,7-hexahydro-6H-pyrazolo[3,4-c]pyridine-6-carboxylate (CAS 1215230-05-9)
- 475662-36-3 Liver PC (CAS 475662-36-3)
- [(3-Chlorophenyl)methyl](prop-2-en-1-yl)amine (CAS 893591-54-3)
- 2-[4-(3-Trifluoromethylphenyl)-1-piperazinyl]propanol (CAS 40004-29-3)
- (2-Fluoro-4-(4-methylpiperidine-1-carbonyl)phenyl)boronic acid (CAS 1449131-89-8)
- 2-Trifluoromethylbenzylmethylsulfone (CAS 886497-88-7)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
Why CATO?
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