4-(4-Bromophenyl)nicotinaldehyde CAS 376646-65-0
| CAS No. | 376646-65-0 |
| Molecular Formula | C12H8BrNO |
| Molecular Weight | 262.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(4-Bromophenyl)nicotinaldehyde (CAS 376646-65-0), molecular formula C12H8BrNO and molecular weight 262.10 g/mol, is a CATO reference standard with documented purity and traceability.
4-(4-Bromophenyl)nicotinaldehyde (C12H8BrNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-(4-Bromophenyl)nicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8BrNO |
| Molecular Weight | 262.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromophenyl Standards
- 6-(2-Bromophenyl)picolinaldehyde (CAS 112432-89-0)
- (4-Bromophenyl)(pyridin-3-yl)methanone (CAS 14548-45-9)
- (4-Bromophenyl)(pyridin-4-yl)methanone (CAS 14548-49-3)
- (2-Bromophenyl)(pyridin-2-yl)methanone (CAS 76160-34-4)
- (2-Bromophenyl)-pyridin-3-ylmethanone (CAS 77744-06-0)
- (3-Bromophenyl)(pyridin-3-yl)methanone (CAS 79362-44-0)
- 4-(3-Bromophenyl)nicotinaldehyde (CAS 376646-64-9)
- 5-(2-Bromophenyl)pyridine-3-carbaldehyde (CAS 887973-68-4)
Recommended Standards
- 4-(5-Bromopyridin-2-yl)benzaldehyde (CAS 910547-57-8)
- 3-Bromo-9H-carbazol-4-ol (CAS 890017-24-0)
- 4-(6-Bromopyridin-2-yl)benzaldehyde (CAS 588727-65-5)
- 3-Bromo-5-[(tetrahydro-2H-pyran-2-yloxy)methyl]isoxazole (CAS 903131-52-2)
- 1-Methoxy-3-nitronaphthalene (CAS 13802-40-9)
- 2-(1H-Indol-5-yl)benzoic acid (CAS 886363-17-3)
- 3-(5-methylfuran-2-yl)morpholine (CAS 1270551-95-5)
- 3-ethyl-octahydro-1H-pyrido[1,2-a]piperazine (CAS 1228682-15-2)
- 3-chloro-N-(4-chloro-3-methoxyphenyl)propanamide (CAS 915920-71-7)
- 2-[4-(3,4-Dichlorobenzyloxy)-phenylethyl Methanesulfonate (CAS 188928-10-1)
- 3-(3,4-dichlorophenoxy)propan-1-ol (CAS 81785-47-9)
- 6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(2,2,2-trichloro-1-hydroxyethyl)hexanamide (CAS 1443664-77-4)
- 3-Methylimidazo[1,5-a]pyridin-6-amine dihydrochloride (CAS 2866334-64-5)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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