Diethynyl(phenyl)phosphine oxide CAS 37755-67-2
| CAS No. | 37755-67-2 |
| Molecular Formula | C10H7OP |
| Molecular Weight | 174.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Diethynyl(phenyl)phosphine oxide.
CATO supplies Diethynyl(phenyl)phosphine oxide (CAS 37755-67-2), a certified reference material (molecular formula C10H7OP, MW 174.14 g/mol) for analytical method development and quality control.
The molecular framework of Diethynyl(phenyl)phosphine oxide (C10H7OP) is characterized by organophosphorus functionality, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7OP |
| Molecular Weight | 174.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
Related Diethynyl Standards
- 1,4-Diethynyl-2-nitrobenzene (CAS 113639-27-3)
- 1,2-Diethynyl-3,4,5,6-tetramethylbenzene (CAS 65103-79-9)
- 1,5-Diethynyl-2,4-difluorobenzene (CAS 1379822-11-3)
- 1,4-Diethynyl-2,3-difluorobenzene (CAS 1430403-93-2)
- 1,4-Diethynyl-2,5-difluorobenzene (CAS 156016-23-8)
- 1,2-diethynyl-4,5-dimethoxybenzene (CAS 170160-98-2)
- 1,4-Diethynyl-2,5-dimethoxybenzene (CAS 74029-40-6)
- 1,5-Diethynyl-2,4-dimethylbenzene (CAS 1379822-09-9)
Recommended Standards
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- methyl(pyridazin-4-ylmethyl)amine hydrochloride (CAS 1788054-87-4)
- 2-Amino-5-methylpyridin-4-ol (CAS 1033203-33-6)
- 3-Oxo-3-(3,4,5-trimethyl-1H-pyrazol-1-yl)propanenitrile (CAS 477710-14-8)
- 2-Chloro-3-cyanobenzene-1-sulfonyl chloride (CAS 1261851-22-2)
- (S)-4-(Benzyloxy)-2-ethyl-4-oxobutanoic acid (CAS 1932079-11-2)
- 3-[5-(2-bromophenyl)-1,3-oxazol-2-yl]propanoic acid (CAS 1016534-16-9)
- Integrin Binding Peptide trifluoroacetate salt (CAS 278792-07-7)
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