4,6-Dihydroxyquinoline-2-carboxylic acid CAS 3778-29-8
| CAS No. | 3778-29-8 |
| Molecular Formula | C10H7NO4 |
| Molecular Weight | 205.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 205.17 g/mol gives 4,6-Dihydroxyquinoline-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4,6-Dihydroxyquinoline-2-carboxylic acid (CAS 3778-29-8), a certified reference material (molecular formula C10H7NO4, MW 205.17 g/mol) for analytical method development and quality control.
4,6-Dihydroxyquinoline-2-carboxylic acid (C10H7NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,6-Dihydroxyquinoline-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7NO4 |
| Molecular Weight | 205.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Dihydroxyquinoline Standards
- 4,8-Dihydroxyquinoline-3-carboxylic acid (CAS 1131580-58-9)
- 6,7-Dihydroxyquinoline-2-carboxylic acid (CAS 122234-87-1)
- 3,4-Dihydroxyquinoline-5-carboxylic acid (CAS 127980-50-1)
- 3,4-Dihydroxyquinoline-2-carboxylic acid (CAS 33925-79-0)
- 4,5-Dihydroxyquinoline-3-carboxylic acid (CAS 79148-46-2)
- 6,8-Dihydroxyquinoline-2-carboxylic acid (CAS 63713-29-1)
- 6,7-Dihydroxyquinoline-3-carboxamide (CAS 146515-41-5)
- Methyl 2,4-dihydroxyquinoline-3-carboxylate (CAS 73776-19-9)
Recommended Standards
- 4-Amino-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS 77289-98-6)
- 4-(Nitromethyl)phthalazin-1-ol (CAS 49546-81-8)
- 4-Hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid (CAS 71706-60-0)
- 3-Nitro-6-(1H-pyrazol-1-yl)pyridin-2-amine (CAS 934992-80-0)
- tert-Butyl (Morpholin-3-ylmethyl)carbamate (CAS 169750-75-8)
- N-(tert-Butyl)-4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 2377607-00-4)
- Dimethyl 3,5-dihydroxyphthalate (CAS 67609-51-2)
- N-(2-Aminocyclohexyl)-2-chloronicotinamide hydrochloride (CAS 1353947-80-4)
- 2-(Aminomethyl)benzoxazole (CAS 101333-98-6)
- 2,2-Dimethyl-3-(4-methylphenyl)propanal (CAS 22490-57-9)
- Tert-butyl 2-(prop-1-en-2-yl)pyrrolidine-1-carboxylate (CAS 1334492-15-7)
- Diphenyl(p-tolyl)sulfonium trifluoromethanesulfonate (CAS 81416-37-7)
- Isometamidium chloride (CAS 34301-55-8)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
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