1-(4-Bromophenyl)-2,3-butadien-1-one CAS 378186-96-0
| CAS No. | 378186-96-0 |
| Molecular Formula | C10H7BrO |
| Molecular Weight | 223.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 223.07 g/mol gives 1-(4-Bromophenyl)-2,3-butadien-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(4-Bromophenyl)-2,3-butadien-1-one (CAS 378186-96-0) is a high-purity analytical reference standard with the molecular formula C10H7BrO and a molecular weight of 223.07 g/mol.
Owing to a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, 1-(4-Bromophenyl)-2,3-butadien-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 223.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7BrO |
| Molecular Weight | 223.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
Related Bromophenyl Standards
- 1-(4-Bromophenyl)-1H-imidazole (CAS 10040-96-7)
- 3-(2-Bromophenyl)-1h-pyrazole (CAS 114382-20-6)
- 4-(2-Bromophenyl)-1h-pyrazole (CAS 1260795-26-3)
- 2-(4-Bromophenyl)furan (CAS 14297-34-8)
- 3-(3-Bromophenyl)pyrazole (CAS 149739-65-1)
- 2-(2-Bromophenyl)imidazole (CAS 162356-38-9)
- 1-(2-Bromophenyl)-1H-imidazole (CAS 190198-35-7)
- 1-(2-Bromophenyl)-2,3-butadien-1-one (CAS 196953-04-5)
Recommended Standards
- 1-(3-Bromophenyl)imidazole (CAS 25372-02-5)
- 1-(5-Bromopyridin-2-yl)cyclopropanecarbonitrile (CAS 827628-15-9)
- 1-(3-Bromophenyl)-1H-pyrazole (CAS 294877-33-1)
- 1-(6-Bromopyridin-3-yl)cyclopropanecarbonitrile (CAS 827628-16-0)
- 1,2- Benzenedic Arboxylic Acid, Dipentylest Er, Branched And Linear (CAS CATO-LPAE111743-HE)
- 3-(2-oxo-1,3-oxazolidin-3-yl)propanoic acid (CAS 876506-51-3)
- n-((4-Methylthiazol-5-yl)methyl)cyclopropanamine (CAS 921075-28-7)
- (1-(4-Ethylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methanol (CAS 678550-05-5)
- 1-(4-Bromobenzyl)piperidin-4-ol (CAS 184921-07-1)
- Ensitrelvir Impurity 4 HCl (CAS 135206-76-7)
- Methyl 4-hydroxytetrahydro-2H-pyran-2-carboxylate (CAS 1818265-13-2)
- L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-2-propyn-1-yl-, 2,5-dioxo-1-pyrrolidinyl ester (CAS 1800210-74-5)
- 3-((2-(Tert-butyl)-5-methylphenoxy)methyl)-4-methoxybenzaldehyde (CAS 832737-62-9)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
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