2-((7-Chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)ethan-1-ol CAS 378201-55-9

Purity 97%+In StockPharmaceutical Standards
CAS No.378201-55-9
Molecular FormulaC8H7ClN4O4
Molecular Weight258.62 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((7-Chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)ethan-1-ol CAS 378201-55-9 chemical structure

Description

2-((7-Chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)ethan-1-ol (CAS 378201-55-9) is a high-purity analytical reference standard with the molecular formula C8H7ClN4O4 and a molecular weight of 258.62 g/mol.

The molecular framework of 2-((7-Chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)ethan-1-ol (C8H7ClN4O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H7ClN4O4
Molecular Weight258.62 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms4

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