7-Fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-ol CAS 379228-59-8

Purity 97%+In StockPharmaceutical Standards
CAS No.379228-59-8
Molecular FormulaC13H13FN2O3
Molecular Weight264.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-ol CAS 379228-59-8 chemical structure

Description

The occurrence of 7-Fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-ol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 7-Fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-ol (CAS 379228-59-8), a certified reference material (molecular formula C13H13FN2O3, MW 264.25 g/mol) for analytical method development and quality control.

The molecular framework of 7-Fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-ol (C13H13FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 7-Fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H13FN2O3
Molecular Weight264.25 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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