4-Chloro-3-(thiophene-2-amido)benzoic acid CAS 379254-57-6
| CAS No. | 379254-57-6 |
| Molecular Formula | C12H8ClNO3S |
| Molecular Weight | 281.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-3-(thiophene-2-amido)benzoic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Chloro-3-(thiophene-2-amido)benzoic acid (CAS 379254-57-6), a certified reference material (molecular formula C12H8ClNO3S, MW 281.71 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H8ClNO3S, 4-Chloro-3-(thiophene-2-amido)benzoic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 281.71 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-3-(thiophene-2-amido)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClNO3S |
| Molecular Weight | 281.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-(((3-Chloro-2-fluorophenyl)amino)methyl)-6-methoxyphenol (CAS 1039879-98-5)
- 4-Chloro-2-(thiophene-2-amido)benzoic acid (CAS 108204-33-7)
- 2-(((2-Chloro-5-fluorophenyl)amino)methyl)-6-methoxyphenol (CAS 1232787-19-7)
- 2-Chloro-6,7-dihydrothieno[2',3':4,5]oxepino[3,2-b]pyridine-9-carboxylic acid (CAS 1282528-90-8)
- 2-(((3-Chloro-4-fluorophenyl)amino)methyl)-6-methoxyphenol (CAS 415968-50-2)
- 2-(4-Chloro-2-fluorophenyl)hexahydro-1H-isoindole-1,3(2H)-dione (CAS 61330-03-8)
- 2-Chloro-5-nitro-N-(2,3,4,5,6-pentadeuteriophenyl)benzamide (CAS 2117730-84-2)
- 2-Chloro-N-((4-fluorophenyl)(1-methyl-1h-imidazol-2-yl)methyl)acetamide (CAS 923730-09-0)
Recommended Standards
- 4-Chloro-2-(4-fluorophenyl)-5-(propylamino)pyridazin-3(2H)-one (CAS 478049-14-8)
- 4-Chloro-N-(4-oxocyclohexa-2,5-dien-1-ylidene)benzenesulfonamide (CAS 38250-73-6)
- 3-Isonicotinoylbenzenesulfonyl chloride (CAS 680618-21-7)
- n1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-n3,n3-dimethylpropane-1,3-diamine (CAS 338406-25-0)
- (2-(3-Methoxyphenyl)pyrimidin-5-yl)boronic acid (CAS 2225154-84-5)
- 2,3-Dichloro-4-methoxybenzoic acid (CAS 55901-80-9)
- Bornaprine (CAS 20448-86-6)
- 5-Bromo-2-methyl-6-(piperidin-1-yl)nicotinic acid (CAS 1443290-27-4)
- 2-{2-Cyclobutyl-7-fluoro-1H-benzo[d]imidazol-1-yl}acetic acid (CAS 1774898-65-5)
- 1-(2-Chloropyridin-4-yl)dodecan-1-one (CAS 898784-80-0)
- 5-(3-(Chloromethyl)-[1,2,4]triazolo[4,3-a]pyridin-8-yl)-3-ethyl-1,2,4-oxadiazole (CAS 1707394-36-2)
- 4-Fluoro-3-(methoxymethyl)phenylboronic acid (CAS 337536-19-3)
- 1-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-ol (CAS 1354949-65-7)
- Neuropeptide Y, human (CAS 98264-90-5)
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