5-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4-phenyl-4h-1,2,4-triazole-3-thiol CAS 379725-33-4

Purity 97%+In StockPharmaceutical Standards
CAS No.379725-33-4
Molecular FormulaC16H13N3O2S
Molecular Weight311.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4-phenyl-4h-1,2,4-triazole-3-thiol CAS 379725-33-4 chemical structure

Description

The molecular framework of 5-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4-phenyl-4h-1,2,4-triazole-3-thiol (C16H13N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

5-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4-phenyl-4h-1,2,4-triazole-3-thiol (CAS 379725-33-4), molecular formula C16H13N3O2S and molecular weight 311.36 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4-phenyl-4h-1,2,4-triazole-3-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H13N3O2S
Molecular Weight311.36 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms3
Sulfur Atoms1

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