3-[3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-phenyl-1H-pyrazol-4-yl]-acrylic acid CAS 379726-46-2
| CAS No. | 379726-46-2 |
| Molecular Formula | C20H16N2O4 |
| Molecular Weight | 348.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-[3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-phenyl-1H-pyrazol-4-yl]-acrylic acid (CAS 379726-46-2), molecular formula C20H16N2O4 and molecular weight 348.35 g/mol, is a CATO reference standard with documented purity and traceability.
3-[3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-phenyl-1H-pyrazol-4-yl]-acrylic acid (C20H16N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 3-[3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-phenyl-1H-pyrazol-4-yl]-acrylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H16N2O4 |
| Molecular Weight | 348.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Dihydro Standards
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- 2-(2,3-Dihydro-benzo[1,4]dioxine-6-sulfonylamino)-4-methylsulfanyl-butyric acid (CAS 1396963-71-5)
- N-(4-(6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl)phenyl)-2-phenoxypropanamide (CAS 1421444-70-3)
- 3-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)-3-[3-(trifluoromethyl)phenyl]propanoic acid (CAS 478260-15-0)
- 3-(3,4-Dihydro-2H-quinoline-1-sulfonyl)-4-methoxy-benzoic acid (CAS 750613-28-6)
- 3,4-Dihydro-2H-1-benzopyran-4-yl N-(4-methylbenzenesulfonyl)carbamate (CAS 866042-86-6)
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Recommended Standards
- 3,3-[(4-Hydroxyphenyl)methylene]bis[4-hydroxybenzaldehyde (CAS 235106-86-2)
- 4-((4-Fluorophenyl)thio)-N-(5-(isoxazol-5-yl)-1,3,4-oxadiazol-2-yl)butanamide (CAS 952822-42-3)
- 3-(5-Methyl-7-oxo-3-phenyl-7H-furo[3,2-g]chromen-6-yl)propanoic acid (CAS 777857-48-4)
- 4-(2,5-Dioxo-3-phenylpyrrolidin-1-yl)-3-fluorobenzenesulfonamide (CAS 30438-06-3)
- ((1s,5s)-3-Azabicyclo[3.1.0]hexan-1-yl)methanol (CAS 1820574-43-3)
- Methyl 3-amino-4-chlorobenzoate hydrochloride (CAS 161796-15-2)
- N-(3-Methyl-5-phenyl-1H-pyrazol-4-yl)nicotinamide (CAS 645418-12-8)
- Methyl 9-(hydroxymethyl)-9H-purine-6-carboxylate (CAS 95121-26-9)
- p-Nitrophenyl decyl ether (CAS 31657-37-1)
- Triethynylphosphine oxide (CAS 33734-02-0)
- (5-(Pyrrolidin-1-ylmethyl)furan-2-yl)methanol (CAS 61481-02-5)
- rel-Ethyl (1R,2S)-1-Amino-2-vinylcyclopropane-1-carboxylate hydrochloride (CAS 259214-54-5)
- Ethyl 1-Cbz-piperidine-4-carboxylate (CAS 160809-38-1)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com