1-(2-Chloro-1,1,2-trifluoroethoxy)butane CAS 380-43-8

Purity 97%+In StockPharmaceutical Standards
CAS No.380-43-8
Molecular FormulaC6H10ClF3O
Molecular Weight190.59 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-Chloro-1,1,2-trifluoroethoxy)butane CAS 380-43-8 chemical structure

Description

1-(2-Chloro-1,1,2-trifluoroethoxy)butane (CAS 380-43-8) is a high-purity analytical reference standard with the molecular formula C6H10ClF3O and a molecular weight of 190.59 g/mol.

The molecular framework of 1-(2-Chloro-1,1,2-trifluoroethoxy)butane (C6H10ClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2-Chloro-1,1,2-trifluoroethoxy)butane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H10ClF3O
Molecular Weight190.59 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1957
Halogen ContentF/Cl-containing

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