2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]acetonitrile CAS 380348-77-6

Purity 97%+In StockPharmaceutical Standards
CAS No.380348-77-6
Molecular FormulaC13H12N2O2S
Molecular Weight260.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]acetonitrile CAS 380348-77-6 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]acetonitrile (CAS 380348-77-6) is a high-purity analytical reference standard with the molecular formula C13H12N2O2S and a molecular weight of 260.31 g/mol.

2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]acetonitrile (C13H12N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), 2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H12N2O2S
Molecular Weight260.31 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2
Sulfur Atoms1

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