1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-3-hydroxy-5-(3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one CAS 380888-58-4
| CAS No. | 380888-58-4 |
| Molecular Formula | C23H20N4O5 |
| Molecular Weight | 432.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-3-hydroxy-5-(3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-3-hydroxy-5-(3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 380888-58-4), molecular formula C23H20N4O5 and molecular weight 432.43 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-3-hydroxy-5-(3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one (C23H20N4O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H20N4O5 |
| Molecular Weight | 432.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related H Standards
- 1-(3-(1H-Imidazol-1-yl)propyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one (CAS 618075-07-3)
- 2-(4-(1H-imidazol-1-yl)phenyl)-6,8-dibromoquinoline (CAS 861210-40-4)
- 1-(3-(1H-Imidazol-1-yl)propyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one (CAS 618075-09-5)
- (4-(4-(1H-Imidazol-1-yl)-6-morpholino-1,3,5-triazin-2-yl)piperazin-1-yl)(thiophen-2-yl)methanone (CAS 1171069-90-1)
- (4-(2-(1H-Imidazol-1-yl)ethoxy)phenyl)-(3-(4-bromophenyl)pyrrolidin-1-yl)methanone (CAS 1951451-77-6)
- 3-((1H-Imidazol-1-yl)methyl)-3-(4-chlorophenyl)-5-(2,6-dichlorophenyl)-2-methylisoxazolidine (CAS 113614-54-3)
- 1-{7-[4-(1H-imidazol-1-yl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-phenylpiperazine (CAS 338403-81-9)
- 1-(3-(1H-Imidazol-1-yl)propyl)-4-(furan-2-carbonyl)-3-hydroxy-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 378212-42-1)
Recommended Standards
- (S)-3-(Fmoc-amino)-3-(3-nitrophenyl)propanoic Acid (CAS 374791-01-2)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-nitrophenyl)propanoic acid (CAS 250740-52-4)
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-nitrophenyl)propanoic acid (CAS 501015-25-4)
- 2-((4-Fluorophenyl)sulfonamido)-4-methyl-N-(3-(trifluoromethyl)phenyl)pentanamide (CAS 317377-98-3)
- 1-Ethynyl-3,5-dimethylcyclohexan-1-ol (CAS 1483917-81-2)
- Ethyl 1-(3-bromo-2-cyanophenyl)piperidine-4-carboxylate (CAS 1260897-03-7)
- 2-Phenyl-4,5,6,7-tetrahydrooxazolo[4,5-c]pyridine (CAS 944897-09-0)
- 6-Piperidin-4-yl-1H-indole (CAS 914223-10-2)
- 6-Amino-2-phenyl-2,5-dihydro-4H-pyrazolo[3,4-c]quinolin-4-one (CAS 1315307-78-8)
- 4-((1,4,8 ,11-Tetraazacyclotetradecan-1-yl) methyl)benzaldehyde (CAS 1254176-45-8)
- 2-(2-Methylphenyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole (CAS 478260-90-1)
- 6-Chloro-N-(2,2-dimethoxyethyl)pyridazin-3-amine (CAS 606135-13-1)
- Benzeneacetic acid, α-(hydroxymethyl)-4-(methoxycarbonyl)- (CAS 2822643-05-8)
- Acetyl Dipeptide-1 (CAS 196604-48-5)
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