1,4-Dichloro-2,2-difluorobutane CAS 381-34-0
| CAS No. | 381-34-0 |
| Molecular Formula | C4H6Cl2F2 |
| Molecular Weight | 162.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,4-Dichloro-2,2-difluorobutane.
CATO supplies 1,4-Dichloro-2,2-difluorobutane (CAS 381-34-0), a certified reference material (molecular formula C4H6Cl2F2, MW 162.99 g/mol) for analytical method development and quality control.
1,4-Dichloro-2,2-difluorobutane (C4H6Cl2F2) contains fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H6Cl2F2 |
| Molecular Weight | 162.99 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
- 1,2-Dichloro-3,3-Difluorobutane (CAS 381-85-1)
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- 3,6-Dichloro-4-methylpyridazine (CAS 19064-64-3)
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Recommended Standards
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- 5,6-Dichloropyridin-2-amine (CAS 1192814-45-1)
- 2-(4-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)phenyl)ethan-1-amine (CAS 384815-61-6)
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- Aminolevulinic Acid Impurity 9 (CAS CATO-C4X-21219)
- 3-[4-(tert-Butyl)-2-chlorophenoxy]pyrrolidinehydrochloride (CAS 1220035-98-2)
- 3-(4-Chloro-1h-pyrazol-1-yl)propanenitrile (CAS 1001500-05-5)
- (2R)-2-Hydroxy-N-methylpropanamide (CAS 133930-09-3)
- tert-Butyl (trans-4-((tetrahydro-2H-pyran-4-yl)amino)cyclohexyl)carbamate (CAS 1228947-20-3)
- 5-(2-Aminothiazol-4-yl)-2-hydroxybenzyl acetate (CAS 890096-19-2)
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